4m83: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| (4 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
== | ==Ensemble refinement of protein crystal structure (2IYF) of macrolide glycosyltransferases OleD complexed with UDP and Erythromycin A== | ||
[[4m83]] is a 2 chain structure with sequence from [ | <StructureSection load='4m83' size='340' side='right'caption='[[4m83]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4m83]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_antibioticus Streptomyces antibioticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M83 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M83 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.698Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ERY:ERYTHROMYCIN+A'>ERY</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m83 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m83 OCA], [https://pdbe.org/4m83 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m83 RCSB], [https://www.ebi.ac.uk/pdbsum/4m83 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m83 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/OLED_STRAT OLED_STRAT] Specifically inactivates oleandomycin via 2'-O-glycosylation using UDP-glucose. | |||
== | ==See Also== | ||
< | *[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Streptomyces antibioticus]] | [[Category: Streptomyces antibioticus]] | ||
[[Category: Bingman | [[Category: Bingman CA]] | ||
[[Category: Helmich | [[Category: Helmich KE]] | ||
[[Category: | [[Category: Martinez iii E]] | ||
[[Category: Olmos | [[Category: Olmos Jr JL]] | ||
[[Category: Phillips | [[Category: Phillips Jr GN]] | ||
[[Category: Singh | [[Category: Singh S]] | ||
[[Category: Thorson | [[Category: Thorson JS]] | ||
[[Category: Wang | [[Category: Wang F]] | ||
[[Category: Xu | [[Category: Xu W]] | ||
Latest revision as of 15:24, 1 March 2024
Ensemble refinement of protein crystal structure (2IYF) of macrolide glycosyltransferases OleD complexed with UDP and Erythromycin AEnsemble refinement of protein crystal structure (2IYF) of macrolide glycosyltransferases OleD complexed with UDP and Erythromycin A
Structural highlights
FunctionOLED_STRAT Specifically inactivates oleandomycin via 2'-O-glycosylation using UDP-glucose. See Also |
| ||||||||||||||||||