4m83: Difference between revisions

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-'''Unreleased structure'''
-The entry 4m83 is ON HOLD
+==Ensemble refinement of protein crystal structure (2IYF) of macrolide glycosyltransferases OleD complexed with UDP and Erythromycin A==
+<StructureSection load='4m83' size='340' side='right'caption='[[4m83]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4m83]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_antibioticus Streptomyces antibioticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M83 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M83 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.698&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ERY:ERYTHROMYCIN+A'>ERY</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m83 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m83 OCA], [https://pdbe.org/4m83 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m83 RCSB], [https://www.ebi.ac.uk/pdbsum/4m83 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m83 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/OLED_STRAT OLED_STRAT] Specifically inactivates oleandomycin via 2'-O-glycosylation using UDP-glucose.
-Authors: Wang, F., Helmich, K.E., Xu, W., Singh, S., Olmos, Jr., J.L., Martinez III, E., Bingman, C.A., Thorson, J.S., Phillips Jr., G.N., Enzyme Discovery for Natural Product Biosynthesis (NatPro)
+==See Also==
+*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
-Description: Ensemble refinement of protein crystal structure (2IYF) of macrolide glycosyltransferases OleD complexed with UDP and Erythromycin A
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Streptomyces antibioticus]]
+[[Category: Bingman CA]]
+[[Category: Helmich KE]]
+[[Category: Martinez iii E]]
+[[Category: Olmos Jr JL]]
+[[Category: Phillips Jr GN]]
+[[Category: Singh S]]
+[[Category: Thorson JS]]
+[[Category: Wang F]]
+[[Category: Xu W]]