4m83: Difference between revisions
New page: '''Unreleased structure''' The entry 4m83 is ON HOLD Authors: Wang, F., Helmich, K.E., Xu, W., Singh, S., Olmos, Jr., J.L., Martinez III, E., Bingman, C.A., Thorson, J.S., Phillips Jr.,... |
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==Ensemble refinement of protein crystal structure (2IYF) of macrolide glycosyltransferases OleD complexed with UDP and Erythromycin A== | |||
<StructureSection load='4m83' size='340' side='right'caption='[[4m83]], [[Resolution|resolution]] 1.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4m83]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_antibioticus Streptomyces antibioticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M83 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M83 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.698Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ERY:ERYTHROMYCIN+A'>ERY</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m83 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m83 OCA], [https://pdbe.org/4m83 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m83 RCSB], [https://www.ebi.ac.uk/pdbsum/4m83 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m83 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/OLED_STRAT OLED_STRAT] Specifically inactivates oleandomycin via 2'-O-glycosylation using UDP-glucose. | |||
==See Also== | |||
*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Streptomyces antibioticus]] | |||
[[Category: Bingman CA]] | |||
[[Category: Helmich KE]] | |||
[[Category: Martinez iii E]] | |||
[[Category: Olmos Jr JL]] | |||
[[Category: Phillips Jr GN]] | |||
[[Category: Singh S]] | |||
[[Category: Thorson JS]] | |||
[[Category: Wang F]] | |||
[[Category: Xu W]] | |||