4l6h: Difference between revisions
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==Crystal structure of the Candida albicans Methionine Synthase in complex with Methotrexate and Homocysteine== | |||
<StructureSection load='4l6h' size='340' side='right'caption='[[4l6h]], [[Resolution|resolution]] 1.75Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4l6h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans_SC5314 Candida albicans SC5314]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L6H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L6H FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HCS:2-AMINO-4-MERCAPTO-BUTYRIC+ACID'>HCS</scene>, <scene name='pdbligand=MTX:METHOTREXATE'>MTX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l6h OCA], [https://pdbe.org/4l6h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l6h RCSB], [https://www.ebi.ac.uk/pdbsum/4l6h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l6h ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/METE_CANAL METE_CANAL] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.[HAMAP-Rule:MF_00172] | |||
==See Also== | |||
*[[Methionine synthase 3D structures|Methionine synthase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Candida albicans SC5314]] | |||
[[Category: Large Structures]] | |||
[[Category: Robertus JD]] | |||
[[Category: Ubhi D]] |