4jql: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-{{STRUCTURE_4jql|  PDB=4jql  |  SCENE=  }}
-===Synthesis of Benzoquinone-Ansamycin-Inspired Macrocyclic Lactams from Shikimic Acid===
-{{ABSTRACT_PUBMED_23554224}}
-==Function==
+==Synthesis of Benzoquinone-Ansamycin-Inspired Macrocyclic Lactams from Shikimic Acid==
-[[http://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>
+<StructureSection load='4jql' size='340' side='right'caption='[[4jql]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4jql]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JQL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JQL FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.72&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=VJ6:VALERJESOMYCIN'>VJ6</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jql OCA], [https://pdbe.org/4jql PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jql RCSB], [https://www.ebi.ac.uk/pdbsum/4jql PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jql ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>
-==About this Structure==
+==See Also==
-[[4jql]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JQL OCA].
+*[[Heat Shock Protein structures|Heat Shock Protein structures]]
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:023554224</ref><references group="xtra"/><references/>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Cameron, M D.]]
+[[Category: Large Structures]]
-[[Category: Hernandez, P.]]
+[[Category: Cameron MD]]
-[[Category: Iqbal, S.]]
+[[Category: Hernandez P]]
-[[Category: Jeso, V.]]
+[[Category: Iqbal S]]
-[[Category: Lograsso, P V.]]
+[[Category: Jeso V]]
-[[Category: Micalizio, G C.]]
+[[Category: Lograsso PV]]
-[[Category: Park, H.]]
+[[Category: Micalizio GC]]
-[[Category: Chaperone]]
+[[Category: Park H]]
-[[Category: Chaperone-inhibitor complex]]
-[[Category: Cytosole]]
-[[Category: Geldanamycin]]
-[[Category: Hsp90]]
-[[Category: Inhibitor design]]
-[[Category: Nucleotide binding domain]]