4iy0: Difference between revisions

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-'''Unreleased structure'''
-The entry 4iy0 is ON HOLD  until Paper Publication
+==Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4==
+<StructureSection load='4iy0' size='340' side='right'caption='[[4iy0]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-Authors: Corral-Rodriguez, M.A., Stuiver, M., Encinar, J.A., Spiwok, V., Gomez-Garcia, I., Oyenarte, I., Ereno-Orbea, J., Terashima, H., Accardi, A., Diercks, T., Muller, D., Martinez-Cruz, L.A.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4iy0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IY0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IY0 FirstGlance]. <br>
-Description: Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4iy0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iy0 OCA], [https://pdbe.org/4iy0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4iy0 RCSB], [https://www.ebi.ac.uk/pdbsum/4iy0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iy0 ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[https://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN] Familial primary hypomagnesemia with normocalcuria and normocalcemia. The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[https://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN] Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Accardi A]]
+[[Category: Corral-Rodriguez MA]]
+[[Category: Diercks T]]
+[[Category: Encinar JA]]
+[[Category: Ereno-Orbea J]]
+[[Category: Gomez-Garcia I]]
+[[Category: Martinez-Cruz LA]]
+[[Category: Muller D]]
+[[Category: Oyenarte I]]
+[[Category: Spiwok V]]
+[[Category: Stuiver M]]
+[[Category: Terashima H]]