4bpv: Difference between revisions
New page: '''Unreleased structure''' The entry 4bpv is ON HOLD until Paper Publication Authors: Banner, D.W., Benz, J., Gsell, B., Stihle, M., Ruf, A., Haap, W. Description: MOUSE CATHEPSIN S WI... |
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The | ==MOUSE CATHEPSIN S WITH COVALENT LIGAND== | ||
<StructureSection load='4bpv' size='340' side='right'caption='[[4bpv]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4bpv]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BPV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BPV FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OFH:(4R)-4-[(2-CHLORO-4-{[(2S)-1,1,1-TRIFLUOROPROPAN-2-YL]OXY}PHENYL)SULFONYL]-N-{1-[(E)-IMINOMETHYL]CYCLOPROPYL}-1-{[1-(TRIFLUOROMETHYL)CYCLOPROPYL]CARBONYL}-L-PROLINAMIDE'>OFH</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bpv OCA], [https://pdbe.org/4bpv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bpv RCSB], [https://www.ebi.ac.uk/pdbsum/4bpv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bpv ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CATS_MOUSE CATS_MOUSE] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. | |||
==See Also== | |||
*[[Cathepsin 3D structures|Cathepsin 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Banner DW]] | |||
[[Category: Benz J]] | |||
[[Category: Gsell B]] | |||
[[Category: Haap W]] | |||
[[Category: Ruf A]] | |||
[[Category: Stihle M]] | |||