4bkp: Difference between revisions

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'''Unreleased structure'''


The entry 4bkp is ON HOLD
==Crystal structure of human GDP-L-fucose synthase with bound NADP==
 
<StructureSection load='4bkp' size='340' side='right'caption='[[4bkp]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
Authors: Vollmar, M., Shafqat, N., Rojkova, A., Krojer, T., Bradley, A., Raynor, J.W., Kavanagh, K., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Oppermann, U., Yue, W.W.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4bkp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BKP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BKP FirstGlance]. <br>
Description: Crystal structure of human GDP-L-fucose synthase with bound NADP
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bkp OCA], [https://pdbe.org/4bkp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bkp RCSB], [https://www.ebi.ac.uk/pdbsum/4bkp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bkp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FCL_HUMAN FCL_HUMAN] Two step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Bountra C]]
[[Category: Bradley A]]
[[Category: Edwards A]]
[[Category: Kavanagh K]]
[[Category: Krojer T]]
[[Category: Oppermann U]]
[[Category: Raynor JW]]
[[Category: Rojkova A]]
[[Category: Shafqat N]]
[[Category: Vollmar M]]
[[Category: Yue WW]]
[[Category: Von Delft F]]

Latest revision as of 14:53, 20 December 2023

Crystal structure of human GDP-L-fucose synthase with bound NADPCrystal structure of human GDP-L-fucose synthase with bound NADP

Structural highlights

4bkp is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.7Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FCL_HUMAN Two step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

4bkp, resolution 2.70Å

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