3oq2: Difference between revisions

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{{STRUCTURE_3oq2|  PDB=3oq2  |  SCENE=  }}
===Structure of a CRISPR associated protein Cas2 from Desulfovibrio vulgaris===
{{ABSTRACT_PUBMED_21139194}}


==Function==
==Structure of a CRISPR associated protein Cas2 from Desulfovibrio vulgaris==
[[http://www.uniprot.org/uniprot/Q72WF4_DESVH Q72WF4_DESVH]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity).[HAMAP-Rule:MF_01471]
<StructureSection load='3oq2' size='340' side='right'caption='[[3oq2]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3oq2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfovibrio_vulgaris_str._Hildenborough Desulfovibrio vulgaris str. Hildenborough]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OQ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OQ2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3oq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oq2 OCA], [https://pdbe.org/3oq2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3oq2 RCSB], [https://www.ebi.ac.uk/pdbsum/3oq2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3oq2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CAS2_DESVH CAS2_DESVH] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).


==About this Structure==
==See Also==
[[3oq2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_vulgaris Desulfovibrio vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OQ2 OCA].
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:021139194</ref><references group="xtra"/><references/>
[[Category: Desulfovibrio vulgaris str. Hildenborough]]
[[Category: Desulfovibrio vulgaris]]
[[Category: Large Structures]]
[[Category: Samai, P.]]
[[Category: Samai P]]
[[Category: Shuman, S.]]
[[Category: Shuman S]]
[[Category: Smith, P.]]
[[Category: Smith P]]
[[Category: Crispr]]
[[Category: Ferredoxin fold]]
[[Category: Immune system]]

Latest revision as of 13:35, 21 February 2024

Structure of a CRISPR associated protein Cas2 from Desulfovibrio vulgarisStructure of a CRISPR associated protein Cas2 from Desulfovibrio vulgaris

Structural highlights

3oq2 is a 2 chain structure with sequence from Desulfovibrio vulgaris str. Hildenborough. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.35Å
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CAS2_DESVH CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).

See Also

3oq2, resolution 1.35Å

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