3n2l: Difference between revisions

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-{{STRUCTURE_3n2l|  PDB=3n2l  |  SCENE=  }}
-===2.1 Angstrom resolution crystal structure of an Orotate Phosphoribosyltransferase (pyrE) from Vibrio cholerae O1 biovar eltor str. N16961===
-==Function==
+==2.1 Angstrom resolution crystal structure of an Orotate Phosphoribosyltransferase (pyrE) from Vibrio cholerae O1 biovar eltor str. N16961==
-[[http://www.uniprot.org/uniprot/PYRE_VIBCH PYRE_VIBCH]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity).
+<StructureSection load='3n2l' size='340' side='right'caption='[[3n2l]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+== Structural highlights ==
-==About this Structure==
+<table><tr><td colspan='2'>[[3n2l]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N2L FirstGlance]. <br>
-[[3n2l]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2L OCA].
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n2l OCA], [https://pdbe.org/3n2l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n2l RCSB], [https://www.ebi.ac.uk/pdbsum/3n2l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n2l ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PYRE_VIBCH PYRE_VIBCH] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n2/3n2l_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3n2l ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
+*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
-[[Category: Orotate phosphoribosyltransferase]]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Vibrio cholerae]]
-[[Category: Anderson, W F.]]
+[[Category: Anderson WF]]
-[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
+[[Category: Dubrovska I]]
-[[Category: Dubrovska, I.]]
+[[Category: Halavaty AS]]
-[[Category: Halavaty, A S.]]
+[[Category: Kwon K]]
-[[Category: Kwon, K.]]
+[[Category: Minasov G]]
-[[Category: Minasov, G.]]
+[[Category: Shuvalova L]]
-[[Category: Shuvalova, L.]]
+[[Category: Winsor J]]
-[[Category: Winsor, J.]]
-[[Category: Center for structural genomics of infectious disease]]
-[[Category: Csgid]]
-[[Category: Glycosyltransferase]]
-[[Category: Infectious disease]]
-[[Category: Magnesium]]
-[[Category: Orotate phosphoribosyltransferase]]
-[[Category: Pyrimidine biosynthesis]]
-[[Category: Pyrimidine ribonucleotide biosynthesis]]
-[[Category: Transferase]]