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== | ==Solution structure of RSGI RUH-063, an N-terminal domain of Syntaxin 12 from human cDNA== | ||
<StructureSection load='2dnx' size='340' side='right'caption='[[2dnx]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2dnx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DNX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DNX FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dnx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dnx OCA], [https://pdbe.org/2dnx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dnx RCSB], [https://www.ebi.ac.uk/pdbsum/2dnx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dnx ProSAT], [https://www.topsan.org/Proteins/RSGI/2dnx TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/STX12_HUMAN STX12_HUMAN] SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dn/2dnx_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dnx ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Syntaxin 3D structures|Syntaxin 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Abe | [[Category: Abe T]] | ||
[[Category: Hirota | [[Category: Hirota H]] | ||
[[Category: Muto | [[Category: Muto Y]] | ||
[[Category: Yokoyama S]] | |||
[[Category: Yokoyama | |||
Latest revision as of 21:45, 29 May 2024
Solution structure of RSGI RUH-063, an N-terminal domain of Syntaxin 12 from human cDNASolution structure of RSGI RUH-063, an N-terminal domain of Syntaxin 12 from human cDNA
Structural highlights
FunctionSTX12_HUMAN SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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