2a1f: Difference between revisions

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[[Image:2a1f.gif|left|200px]]<br /><applet load="2a1f" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2a1f, resolution 2.10&Aring;" />
'''Crystal Structure of Uridylate kinase'''<br />


==About this Structure==
==Crystal Structure of Uridylate kinase==
2A1F is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A1F OCA].  
<StructureSection load='2a1f' size='340' side='right'caption='[[2a1f]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2a1f]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A1F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A1F FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a1f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a1f OCA], [https://pdbe.org/2a1f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a1f RCSB], [https://www.ebi.ac.uk/pdbsum/2a1f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a1f ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2a1f TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PYRH_HAEIN PYRH_HAEIN] Catalyzes the reversible phosphorylation of UMP to UDP.<ref>PMID:17210578</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a1/2a1f_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a1f ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Uridylate kinase|Uridylate kinase]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Haemophilus influenzae]]
[[Category: Haemophilus influenzae]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Burley, S K.]]
[[Category: Burley SK]]
[[Category: Gorman, J.]]
[[Category: Gorman J]]
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
[[Category: Shapiro L]]
[[Category: Shapiro, L.]]
[[Category: new york structural genomix research consortium]]
[[Category: nysgxrc]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: pyrh]]
[[Category: structural genomics]]
[[Category: uridylate kinase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:22:41 2008''

Latest revision as of 10:17, 23 August 2023

Crystal Structure of Uridylate kinaseCrystal Structure of Uridylate kinase

Structural highlights

2a1f is a 6 chain structure with sequence from Haemophilus influenzae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

PYRH_HAEIN Catalyzes the reversible phosphorylation of UMP to UDP.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Evrin C, Straut M, Slavova-Azmanova N, Bucurenci N, Onu A, Assairi L, Ionescu M, Palibroda N, Barzu O, Gilles AM. Regulatory mechanisms differ in UMP kinases from gram-negative and gram-positive bacteria. J Biol Chem. 2007 Mar 9;282(10):7242-53. Epub 2007 Jan 8. PMID:17210578 doi:http://dx.doi.org/10.1074/jbc.M606963200

2a1f, resolution 2.10Å

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