4hyk: Difference between revisions
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==Dbh Ternary Complex (substrates partially disordered)== | |||
<StructureSection load='4hyk' size='340' side='right'caption='[[4hyk]], [[Resolution|resolution]] 2.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4hyk]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfolobus_acidocaldarius_DSM_639 Sulfolobus acidocaldarius DSM 639] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HYK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HYK FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.802Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hyk OCA], [https://pdbe.org/4hyk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hyk RCSB], [https://www.ebi.ac.uk/pdbsum/4hyk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hyk ProSAT]</span></td></tr> | |||
== | </table> | ||
[[4hyk]] is a 3 chain structure with sequence from [ | == Function == | ||
[https://www.uniprot.org/uniprot/DPO4_SULAC DPO4_SULAC] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis (By similarity). | |||
==See Also== | ==See Also== | ||
*[[DNA polymerase|DNA polymerase]] | *[[DNA polymerase 3D structures|DNA polymerase 3D structures]] | ||
[[Category: | __TOC__ | ||
[[Category: Sulfolobus acidocaldarius | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Sulfolobus acidocaldarius DSM 639]] | ||
[[Category: | [[Category: Synthetic construct]] | ||
[[Category: Pata JD]] | |||
[[Category: Wilson RC]] | |||
Latest revision as of 14:48, 1 March 2024
Dbh Ternary Complex (substrates partially disordered)Dbh Ternary Complex (substrates partially disordered)
Structural highlights
FunctionDPO4_SULAC Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis (By similarity). See Also |
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