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[[Image:3exc.png|left|200px]]


{{STRUCTURE_3exc|  PDB=3exc  |  SCENE=  }}
==Structure of the RNA'se SSO8090 from Sulfolobus solfataricus==
 
<StructureSection load='3exc' size='340' side='right'caption='[[3exc]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
===Structure of the RNA'se SSO8090 from Sulfolobus solfataricus===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3exc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EXC FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
[[3exc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXC OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3exc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3exc OCA], [https://pdbe.org/3exc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3exc RCSB], [https://www.ebi.ac.uk/pdbsum/3exc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3exc ProSAT], [https://www.topsan.org/Proteins/MCSG/3exc TOPSAN]</span></td></tr>
[[Category: Sulfolobus solfataricus]]
</table>
[[Category: Edwards, A M.]]
== Function ==
[[Category: Joachimiak, A.]]
[https://www.uniprot.org/uniprot/CAS2B_SACS2 CAS2B_SACS2] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).<ref>PMID:18482976</ref>
[[Category: Kagan, O.]]
== Evolutionary Conservation ==
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Onopriyenko, O.]]
Check<jmol>
[[Category: Savchenko, A.]]
  <jmolCheckbox>
[[Category: Singer, A U.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ex/3exc_consurf.spt"</scriptWhenChecked>
[[Category: Skarina, T.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Tan, K.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Yakunin, A F.]]
  </jmolCheckbox>
[[Category: Catalytic aspartate]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3exc ConSurf].
[[Category: Dimer]]
<div style="clear:both"></div>
[[Category: Double split beta-alpha-beta fold]]
== References ==
[[Category: Ferredoxin fold]]
<references/>
[[Category: Hydrolase]]
__TOC__
[[Category: Mcsg]]
</StructureSection>
[[Category: Midwest center for structural genomic]]
[[Category: Large Structures]]
[[Category: Protein structure initiative]]
[[Category: Saccharolobus solfataricus]]
[[Category: Psi-2]]
[[Category: Edwards AM]]
[[Category: Rna'ase]]
[[Category: Joachimiak A]]
[[Category: Kagan O]]
[[Category: Onopriyenko O]]
[[Category: Savchenko A]]
[[Category: Singer AU]]
[[Category: Skarina T]]
[[Category: Tan K]]
[[Category: Yakunin AF]]

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