4ilr: Difference between revisions
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New page: '''Unreleased structure''' The entry 4ilr is ON HOLD Authors: Shao, Y,, Li, H Description: Recognition and Cleavage of a non-structured CRISPR RNA by its Processing Endoribonuclease Ca... |
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==Recognition and Cleavage of a non-structured CRISPR RNA by its Processing Endoribonuclease Cas6== | |||
<StructureSection load='4ilr' size='340' side='right'caption='[[4ilr]], [[Resolution|resolution]] 3.09Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4ilr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ILR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ILR FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.088Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ilr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ilr OCA], [https://pdbe.org/4ilr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ilr RCSB], [https://www.ebi.ac.uk/pdbsum/4ilr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ilr ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CAS6B_SACS2 CAS6B_SACS2] CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease, generating an 8 base-long tag known as the 5' handle.<ref>PMID:21507944</ref> | |||
==See Also== | |||
*[[Endonuclease 3D structures|Endonuclease 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharolobus solfataricus P2]] | |||
[[Category: Li H]] | |||
[[Category: Shao Y]] | |||
Latest revision as of 14:57, 1 March 2024
Recognition and Cleavage of a non-structured CRISPR RNA by its Processing Endoribonuclease Cas6Recognition and Cleavage of a non-structured CRISPR RNA by its Processing Endoribonuclease Cas6
Structural highlights
FunctionCAS6B_SACS2 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease, generating an 8 base-long tag known as the 5' handle.[1] See AlsoReferences
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