3dlh: Difference between revisions

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[[Image:3dlh.png|left|200px]]


{{STRUCTURE_3dlh|  PDB=3dlh  |  SCENE=  }}
==Crystal structure of the guide-strand-containing Argonaute protein silencing complex==
 
<StructureSection load='3dlh' size='340' side='right'caption='[[3dlh]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
===Crystal structure of the guide-strand-containing Argonaute protein silencing complex===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3dlh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB27 Thermus thermophilus HB27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DLH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DLH FirstGlance]. <br>
{{ABSTRACT_PUBMED_18754009}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dlh OCA], [https://pdbe.org/3dlh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dlh RCSB], [https://www.ebi.ac.uk/pdbsum/3dlh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dlh ProSAT]</span></td></tr>
[[3dlh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DLH OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q746M7_THET2 Q746M7_THET2]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dl/3dlh_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dlh ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[RNA Interference|RNA Interference]]
*[[Argonaute 3D structures|Argonaute 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:018754009</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus HB27]]
[[Category: Patel, D J.]]
[[Category: Patel DJ]]
[[Category: Sheng, G.]]
[[Category: Sheng G]]
[[Category: Wang, Y.]]
[[Category: Wang Y]]
[[Category: Argonaute]]
[[Category: Nucleic acid binding protein-dna complex]]
[[Category: Protein-dna complex]]

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