2z8h: Difference between revisions

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[[Image:2z8h.png|left|200px]]


{{STRUCTURE_2z8h|  PDB=2z8h  |  SCENE=  }}
==Structure of mouse Bach1 BTB domain==
 
<StructureSection load='2z8h' size='340' side='right'caption='[[2z8h]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
===Structure of mouse Bach1 BTB domain===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2z8h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z8H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z8H FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z8h OCA], [https://pdbe.org/2z8h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z8h RCSB], [https://www.ebi.ac.uk/pdbsum/2z8h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z8h ProSAT]</span></td></tr>
[[2z8h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z8H OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/BACH1_MOUSE BACH1_MOUSE] Transcriptional regulator that acts as repressor or activator. Binds, in vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z8/2z8h_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z8h ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Ito, N.]]
[[Category: Ito N]]
[[Category: Murayama, K.]]
[[Category: Murayama K]]
[[Category: Activator]]
[[Category: Btb]]
[[Category: Disulfide bond]]
[[Category: Dna-binding]]
[[Category: Nucleus]]
[[Category: Phosphorylation]]
[[Category: Poz]]
[[Category: Repressor]]
[[Category: Transcription]]
[[Category: Transcription regulation]]

Latest revision as of 12:39, 6 November 2024

Structure of mouse Bach1 BTB domainStructure of mouse Bach1 BTB domain

Structural highlights

2z8h is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.5Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

BACH1_MOUSE Transcriptional regulator that acts as repressor or activator. Binds, in vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2z8h, resolution 2.50Å

Drag the structure with the mouse to rotate

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