3db5: Difference between revisions

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[[Image:3db5.png|left|200px]]


{{STRUCTURE_3db5|  PDB=3db5  |  SCENE=  }}
==Crystal structure of methyltransferase domain of human PR domain-containing protein 4==
 
<StructureSection load='3db5' size='340' side='right'caption='[[3db5]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
===Crystal structure of methyltransferase domain of human PR domain-containing protein 4===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3db5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DB5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DB5 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
[[3db5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DB5 OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3db5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3db5 OCA], [https://pdbe.org/3db5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3db5 RCSB], [https://www.ebi.ac.uk/pdbsum/3db5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3db5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PRDM4_HUMAN PRDM4_HUMAN] May function as a transcription factor involved in cell differentiation.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/db/3db5_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3db5 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Amaya, M F.]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H.]]
[[Category: Amaya MF]]
[[Category: Bochkarev, A.]]
[[Category: Arrowsmith CH]]
[[Category: Bountra, C.]]
[[Category: Bochkarev A]]
[[Category: Edwards, A M.]]
[[Category: Bountra C]]
[[Category: Loppnau, P.]]
[[Category: Edwards AM]]
[[Category: Min, J.]]
[[Category: Loppnau P]]
[[Category: Plotnikov, A N.]]
[[Category: Min J]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Plotnikov AN]]
[[Category: Weigelt, J.]]
[[Category: Weigelt J]]
[[Category: Wu, H.]]
[[Category: Wu H]]
[[Category: Zeng, H.]]
[[Category: Zeng H]]
[[Category: Dna-binding]]
[[Category: Metal-binding]]
[[Category: Methyltransferase]]
[[Category: Nucleus]]
[[Category: Prdm4]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transferase]]
[[Category: Zinc-finger]]

Latest revision as of 12:47, 6 November 2024

Crystal structure of methyltransferase domain of human PR domain-containing protein 4Crystal structure of methyltransferase domain of human PR domain-containing protein 4

Structural highlights

3db5 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.15Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PRDM4_HUMAN May function as a transcription factor involved in cell differentiation.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

3db5, resolution 2.15Å

Drag the structure with the mouse to rotate

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OCA