3db5: Difference between revisions

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-[[Image:3db5.png|left|200px]]
-{{STRUCTURE_3db5|  PDB=3db5  |  SCENE=  }}
+==Crystal structure of methyltransferase domain of human PR domain-containing protein 4==
+<StructureSection load='3db5' size='340' side='right'caption='[[3db5]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
-===Crystal structure of methyltransferase domain of human PR domain-containing protein 4===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3db5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DB5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DB5 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-[[3db5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DB5 OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3db5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3db5 OCA], [https://pdbe.org/3db5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3db5 RCSB], [https://www.ebi.ac.uk/pdbsum/3db5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3db5 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PRDM4_HUMAN PRDM4_HUMAN] May function as a transcription factor involved in cell differentiation.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/db/3db5_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3db5 ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Amaya, M F.]]
+[[Category: Large Structures]]
-[[Category: Arrowsmith, C H.]]
+[[Category: Amaya MF]]
-[[Category: Bochkarev, A.]]
+[[Category: Arrowsmith CH]]
-[[Category: Bountra, C.]]
+[[Category: Bochkarev A]]
-[[Category: Edwards, A M.]]
+[[Category: Bountra C]]
-[[Category: Loppnau, P.]]
+[[Category: Edwards AM]]
-[[Category: Min, J.]]
+[[Category: Loppnau P]]
-[[Category: Plotnikov, A N.]]
+[[Category: Min J]]
-[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Plotnikov AN]]
-[[Category: Weigelt, J.]]
+[[Category: Weigelt J]]
-[[Category: Wu, H.]]
+[[Category: Wu H]]
-[[Category: Zeng, H.]]
+[[Category: Zeng H]]
-[[Category: Dna-binding]]
-[[Category: Metal-binding]]
-[[Category: Methyltransferase]]
-[[Category: Nucleus]]
-[[Category: Prdm4]]
-[[Category: Sgc]]
-[[Category: Structural genomic]]
-[[Category: Structural genomics consortium]]
-[[Category: Transcription]]
-[[Category: Transcription regulation]]
-[[Category: Transferase]]
-[[Category: Zinc-finger]]