3clp: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
m Protected "3clp" [edit=sysop:move=sysop]
No edit summary
 
(6 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:3clp.png|left|200px]]


{{STRUCTURE_3clp| PDB=3clp | SCENE= }}
==M. loti cyclic-nucleotide binding domain mutant 2==
<StructureSection load='3clp' size='340' side='right'caption='[[3clp]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3clp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesorhizobium_loti Mesorhizobium loti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CLP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CLP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3clp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3clp OCA], [https://pdbe.org/3clp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3clp RCSB], [https://www.ebi.ac.uk/pdbsum/3clp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3clp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CNGK1_RHILO CNGK1_RHILO] Cyclic nucleotide-regulated potassium channel activated by cAMP.<ref>PMID:15550244</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cl/3clp_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3clp ConSurf].
<div style="clear:both"></div>


===M. loti cyclic-nucleotide binding domain mutant 2===
==See Also==
 
*[[Ion channels 3D structures|Ion channels 3D structures]]
{{ABSTRACT_PUBMED_18619611}}
== References ==
 
<references/>
==About this Structure==
__TOC__
[[3clp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mesorhizobium_loti Mesorhizobium loti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CLP OCA].
</StructureSection>
 
[[Category: Large Structures]]
==Reference==
<ref group="xtra">PMID:018619611</ref><references group="xtra"/>
[[Category: Mesorhizobium loti]]
[[Category: Mesorhizobium loti]]
[[Category: Altieri, S L.]]
[[Category: Altieri SL]]
[[Category: Clayton, G M.]]
[[Category: Clayton GM]]
[[Category: Morais-Cabral, J H.]]
[[Category: Morais-Cabral JH]]
[[Category: Thomas, L R.]]
[[Category: Thomas LR]]
[[Category: Membrane protein]]
[[Category: Mlotik1 cyclic-nucleotide binding domain mutant 2. cyclic-amp bound]]

Latest revision as of 12:36, 21 February 2024

M. loti cyclic-nucleotide binding domain mutant 2M. loti cyclic-nucleotide binding domain mutant 2

Structural highlights

3clp is a 2 chain structure with sequence from Mesorhizobium loti. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CNGK1_RHILO Cyclic nucleotide-regulated potassium channel activated by cAMP.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Clayton GM, Silverman WR, Heginbotham L, Morais-Cabral JH. Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel. Cell. 2004 Nov 24;119(5):615-27. PMID:15550244 doi:10.1016/j.cell.2004.10.030

3clp, resolution 2.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=3clp&oldid=4063946"