3aef: Difference between revisions

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[[Image:3aef.png|left|200px]]


{{STRUCTURE_3aef| PDB=3aef | SCENE= }}
==Crystal structure of porcine heart mitochondrial complex II with an empty quinone-binding pocket==
<StructureSection load='3aef' size='340' side='right'caption='[[3aef]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3aef]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AEF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AEF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPH:L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE'>EPH</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3aef FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aef OCA], [https://pdbe.org/3aef PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3aef RCSB], [https://www.ebi.ac.uk/pdbsum/3aef PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3aef ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SDHA_PIG SDHA_PIG] Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor (By similarity).


===Crystal structure of porcine heart mitochondrial complex II with an empty quinone-binding pocket===
==See Also==
 
*[[Succinate dehydrogenase 3D structures|Succinate dehydrogenase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[3aef]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AEF OCA].
[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
[[Category: Harada, S.]]
[[Category: Harada S]]
[[Category: Honma, T.]]
[[Category: Honma T]]
[[Category: Inaoka, D K.]]
[[Category: Inaoka DK]]
[[Category: Inoue, M.]]
[[Category: Inoue M]]
[[Category: Kido, Y.]]
[[Category: Kido Y]]
[[Category: Kita, K.]]
[[Category: Kita K]]
[[Category: Mao, J.]]
[[Category: Mao J]]
[[Category: Matsuoka, S.]]
[[Category: Matsuoka S]]
[[Category: Omori, J.]]
[[Category: Omori J]]
[[Category: Osanai, A.]]
[[Category: Osanai A]]
[[Category: Sakamoto, K.]]
[[Category: Sakamoto K]]
[[Category: Sasaki, T.]]
[[Category: Sasaki T]]
[[Category: Shindo, M.]]
[[Category: Shindo M]]
[[Category: Tanaka, A.]]
[[Category: Tanaka A]]
[[Category: Electron transport]]
[[Category: Fad-binding protein]]
[[Category: Heme]]
[[Category: Inhibitor]]
[[Category: Iron]]
[[Category: Iron-sulfur]]
[[Category: Metal-binding]]
[[Category: Mitochondrion]]
[[Category: Mitochondrion inner membrane]]
[[Category: Oxidoreductase]]
[[Category: Respiratory complex ii]]
[[Category: Transit peptide]]
[[Category: Transmembrane]]
[[Category: Transport]]
[[Category: Tricarboxylic acid cycle]]

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