2kax: Difference between revisions

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-[[Image:2kax.png|left|200px]]
-{{STRUCTURE_2kax|  PDB=2kax  |  SCENE=  }}
+==Solution structure and dynamics of S100A5 in the apo and Ca2+ -bound states==
+<StructureSection load='2kax' size='340' side='right'caption='[[2kax]]' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2kax]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KAX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KAX FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kax OCA], [https://pdbe.org/2kax PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kax RCSB], [https://www.ebi.ac.uk/pdbsum/2kax PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kax ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/S10A5_HUMAN S10A5_HUMAN] Binds calcium, zinc and copper. One subunit can simultaneously bind 2 calcium ions or 2 copper ions plus 1 zinc ion. Calcium and copper ions compete for the same binding sites.<ref>PMID:10882717</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ka/2kax_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kax ConSurf].
+<div style="clear:both"></div>
-===Solution structure and dynamics of S100A5 in the apo and Ca2+ -bound states===
+==See Also==
+*[[S100 proteins 3D structures|S100 proteins 3D structures]]
-{{ABSTRACT_PUBMED_19536568}}
+== References ==
+<references/>
-==About this Structure==
+__TOC__
-[[2kax]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KAX OCA].
+</StructureSection>
-==Reference==
-<ref group="xtra">PMID:019536568</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Bertini, I.]]
+[[Category: Large Structures]]
-[[Category: Gupta, S Das.]]
+[[Category: Bertini I]]
-[[Category: Hu, X.]]
+[[Category: Das Gupta S]]
-[[Category: Karavelas, T.]]
+[[Category: Hu X]]
-[[Category: Luchinat, C.]]
+[[Category: Karavelas T]]
-[[Category: Parigi, G.]]
+[[Category: Luchinat C]]
-[[Category: SPINE, Structural Proteomics in Europe.]]
+[[Category: Parigi G]]
-[[Category: Yuan, J.]]
+[[Category: Yuan J]]
-[[Category: Calcium binding protien]]
-[[Category: Ef-hand]]
-[[Category: Metal binding protein]]
-[[Category: S100a5]]
-[[Category: Spine]]
-[[Category: Spine2]]
-[[Category: Structural genomic]]
-[[Category: Structural proteomics in europe]]