2kre: Difference between revisions

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OCA

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-[[Image:2kre.png|left|200px]]
-{{STRUCTURE_2kre|  PDB=2kre  |  SCENE=  }}
+==Solution structure of E4B/UFD2A U-Box domain==
+<StructureSection load='2kre' size='340' side='right'caption='[[2kre]]' scene=''>
-===Solution structure of E4B/UFD2A U-Box domain===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2kre]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRE FirstGlance]. <br>
-{{ABSTRACT_PUBMED_20696396}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kre OCA], [https://pdbe.org/2kre PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kre RCSB], [https://www.ebi.ac.uk/pdbsum/2kre PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kre ProSAT]</span></td></tr>
-==About this Structure==
+</table>
-[[2kre]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRE OCA].
+== Function ==
+[https://www.uniprot.org/uniprot/UBE4B_HUMAN UBE4B_HUMAN] Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3 (By similarity).
-==Reference==
+== Evolutionary Conservation ==
-<ref group="xtra">PMID:020696396</ref><references group="xtra"/>
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kr/2kre_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kre ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Botuyan, M.]]
+[[Category: Large Structures]]
-[[Category: Mer, G.]]
+[[Category: Botuyan M]]
-[[Category: Nomine, Y.]]
+[[Category: Mer G]]
-[[Category: Wasielewski, E.]]
+[[Category: Nomine Y]]
-[[Category: E3 ubiquitin ligase]]
+[[Category: Wasielewski E]]
-[[Category: E4 polyubiquitin chain elongation factor]]
-[[Category: Phosphoprotein]]
-[[Category: Protein binding]]
-[[Category: U-box domain]]
-[[Category: Ubl conjugation pathway]]