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[[Image:1w6z.gif|left|200px]]<br /><applet load="1w6z" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1w6z, resolution 1.65&Aring;" />
'''HIGH ENERGY TETRAGONAL LYSOZYME X-RAY STRUCTURE'''<br />


==About this Structure==
==High Energy Tetragonal Lysozyme X-ray Structure==
1W6Z is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=HO3:'>HO3</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] Known structural/functional Site: <scene name='pdbsite=AC1:Cl+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W6Z OCA].  
<StructureSection load='1w6z' size='340' side='right'caption='[[1w6z]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
[[Category: Lysozyme]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[1w6z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W6Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W6Z FirstGlance]. <br>
[[Category: Aslantas, M.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
[[Category: Dimichiel, M.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HO3:HOLMIUM+(III)+ATOM'>HO3</scene></td></tr>
[[Category: Honkimaki, V.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w6z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w6z OCA], [https://pdbe.org/1w6z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w6z RCSB], [https://www.ebi.ac.uk/pdbsum/1w6z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w6z ProSAT]</span></td></tr>
[[Category: Jakoncic, J.]]
</table>
[[Category: Stojanoff, V.]]
== Function ==
[[Category: CL]]
[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
[[Category: HO3]]
== Evolutionary Conservation ==
[[Category: bacteriolytic enzyme]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: direct protein sequencing]]
Check<jmol>
[[Category: energy]]
  <jmolCheckbox>
[[Category: glycosidase]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w6/1w6z_consurf.spt"</scriptWhenChecked>
[[Category: high]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: holmium]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: hydrolase]]
  </jmolCheckbox>
[[Category: kedge]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1w6z ConSurf].
[[Category: lysozyme]]
<div style="clear:both"></div>
[[Category: signal]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:41:07 2008''
==See Also==
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Aslantas M]]
[[Category: Di Michiel M]]
[[Category: Honkimaki V]]
[[Category: Jakoncic J]]
[[Category: Stojanoff V]]

Latest revision as of 11:54, 6 November 2024

High Energy Tetragonal Lysozyme X-ray StructureHigh Energy Tetragonal Lysozyme X-ray Structure

Structural highlights

1w6z is a 1 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.65Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LYSC_CHICK Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T. Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. Gene. 2012 Jan 15;492(1):244-9. doi: 10.1016/j.gene.2011.10.021. Epub 2011 Oct, 25. PMID:22044478 doi:10.1016/j.gene.2011.10.021

1w6z, resolution 1.65Å

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