2ogf: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
No edit summary
No edit summary
 
(8 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:2ogf.png|left|200px]]


{{STRUCTURE_2ogf|  PDB=2ogf  |  SCENE=  }}
==Crystal structure of protein MJ0408 from Methanococcus jannaschii, Pfam DUF372==
 
<StructureSection load='2ogf' size='340' side='right'caption='[[2ogf]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
===Crystal structure of protein MJ0408 from Methanococcus jannaschii, Pfam DUF372===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2ogf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OGF FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=OXG:8-OXOGUANINE'>OXG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[2ogf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGF OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ogf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogf OCA], [https://pdbe.org/2ogf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ogf RCSB], [https://www.ebi.ac.uk/pdbsum/2ogf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ogf ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2ogf TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MPTD_METJA MPTD_METJA] Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).[HAMAP-Rule:MF_02130]<ref>PMID:22931285</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/og/2ogf_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ogf ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Almo, S C.]]
[[Category: Almo SC]]
[[Category: Burley, S K.]]
[[Category: Burley SK]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
[[Category: Ramagopal UA]]
[[Category: Ramagopal, U A.]]
[[Category: Sauder JM]]
[[Category: Sauder, J M.]]
[[Category: Toro R]]
[[Category: Toro, R.]]
[[Category: New york sgx research center for structural genomic]]
[[Category: Nysgxrc]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Structural genomic]]
[[Category: Unknown function]]

Latest revision as of 13:38, 30 August 2023

Crystal structure of protein MJ0408 from Methanococcus jannaschii, Pfam DUF372Crystal structure of protein MJ0408 from Methanococcus jannaschii, Pfam DUF372

Structural highlights

2ogf is a 4 chain structure with sequence from Methanocaldococcus jannaschii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.89Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

MPTD_METJA Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).[HAMAP-Rule:MF_02130][1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. de Crecy-Lagard V, Phillips G, Grochowski LL, El Yacoubi B, Jenney F, Adams MW, Murzin AG, White RH. Comparative genomics guided discovery of two missing archaeal enzyme families involved in the biosynthesis of the pterin moiety of tetrahydromethanopterin and tetrahydrofolate. ACS Chem Biol. 2012 Nov 16;7(11):1807-16. doi: 10.1021/cb300342u. Epub 2012 Sep, 7. PMID:22931285 doi:http://dx.doi.org/10.1021/cb300342u

2ogf, resolution 1.89Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA