2fkk: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:2fkk.png|left|200px]]
-{{STRUCTURE_2fkk|  PDB=2fkk  |  SCENE=  }}
+==Crystal structure of the C-terminal domain of the bacteriophage T4 gene product 10==
+<StructureSection load='2fkk' size='340' side='right'caption='[[2fkk]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
-===Crystal structure of the C-terminal domain of the bacteriophage T4 gene product 10===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2fkk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FKK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FKK FirstGlance]. <br>
-{{ABSTRACT_PUBMED_16554069}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO3:PHOSPHITE+ION'>PO3</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fkk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fkk OCA], [https://pdbe.org/2fkk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fkk RCSB], [https://www.ebi.ac.uk/pdbsum/2fkk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fkk ProSAT]</span></td></tr>
-[[2fkk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FKK OCA].
+</table>
+== Function ==
-==Reference==
+[https://www.uniprot.org/uniprot/BP10_BPT4 BP10_BPT4] Baseplate protein that is part of the baseplate wedge and that connects the short tail fibers to the baseplate (PubMed:16554069). During infection, the baseplate undergoes a conformational change from a dome-shaped to a star-shaped structure. At this point, gp10 rotates and acts as a lever that unfolds the short tail fibers, which then interact with host cell surface receptors. Involved in the tail assembly.<ref>PMID:16554069</ref> <ref>PMID:21129200</ref>
-<ref group="xtra">PMID:016554069</ref><references group="xtra"/>
+== Evolutionary Conservation ==
-[[Category: Enterobacteria phage t4]]
+[[Image:Consurf_key_small.gif|200px|right]]
-[[Category: Leiman, P G.]]
+Check<jmol>
-[[Category: Mesyanzhinov, V V.]]
+  <jmolCheckbox>
-[[Category: Rossmann, M G.]]
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fk/2fkk_consurf.spt"</scriptWhenChecked>
-[[Category: Shneider, M M.]]
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-[[Category: Bacteriophage t4]]
+    <text>to colour the structure by Evolutionary Conservation</text>
-[[Category: Baseplate]]
+  </jmolCheckbox>
-[[Category: Evolution]]
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fkk ConSurf].
-[[Category: Gp10]]
+<div style="clear:both"></div>
-[[Category: Structural comparison]]
+== References ==
-[[Category: Tail]]
+<references/>
-[[Category: Viral protein]]
+__TOC__
+</StructureSection>
+[[Category: Escherichia virus T4]]
+[[Category: Large Structures]]
+[[Category: Leiman PG]]
+[[Category: Mesyanzhinov VV]]
+[[Category: Rossmann MG]]
+[[Category: Shneider MM]]