2dku: Difference between revisions

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-[[Image:2dku.png|left|200px]]
-{{STRUCTURE_2dku|  PDB=2dku  |  SCENE=  }}
+==Solution structure of the third Ig-like domain of human KIAA1556 protein==
+<StructureSection load='2dku' size='340' side='right'caption='[[2dku]]' scene=''>
-===Solution structure of the third Ig-like domain of human KIAA1556 protein===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2dku]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DKU FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dku OCA], [https://pdbe.org/2dku PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dku RCSB], [https://www.ebi.ac.uk/pdbsum/2dku PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dku ProSAT], [https://www.topsan.org/Proteins/RSGI/2dku TOPSAN]</span></td></tr>
-[[2dku]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKU OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/OBSCN_HUMAN OBSCN_HUMAN] Involved in myofibrillogenesis. Seems to be involved in assembly of myosin into sarcomeric A bands in striated muscle. Isoform 3 together with ANK1 isoform Mu17/Ank1.5 may provide a molecular link between the sarcoplasmic reticulum and myofibrils.<ref>PMID:11448995</ref> <ref>PMID:16205939</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/2dku_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dku ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Group:MUZIC:Obscurin|MUZIC:Obscurin]]
+*[[Obscurin|Obscurin]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Hayashi, F.]]
+[[Category: Large Structures]]
-[[Category: Kurosaki, C.]]
+[[Category: Hayashi F]]
-[[Category: Nagashima, K.]]
+[[Category: Kurosaki C]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+[[Category: Nagashima K]]
-[[Category: Yokoyama, S.]]
+[[Category: Yokoyama S]]
-[[Category: Yoshida, M.]]
+[[Category: Yoshida M]]
-[[Category: Beta-sandwich]]
+[[Category: Z-disk]]
-[[Category: Contractile protein]]
-[[Category: Ig-fold]]
-[[Category: National project on protein structural and functional analyse]]
-[[Category: Nppsfa]]
-[[Category: Obscurin]]
-[[Category: Riken structural genomics/proteomics initiative]]
-[[Category: Rsgi]]
-[[Category: Structural genomic]]