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[[Image:2ecc.png|left|200px]]


{{STRUCTURE_2ecc|  PDB=2ecc  |  SCENE=  }}
==Solution Structure of the second Homeobox Domain of Human Homeodomain Leucine Zipper-Encoding Gene (Homez)==
 
<StructureSection load='2ecc' size='340' side='right'caption='[[2ecc]]' scene=''>
===Solution Structure of the second Homeobox Domain of Human Homeodomain Leucine Zipper-Encoding Gene (Homez)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2ecc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1wjh 1wjh]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ECC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ECC FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ecc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ecc OCA], [https://pdbe.org/2ecc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ecc RCSB], [https://www.ebi.ac.uk/pdbsum/2ecc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ecc ProSAT], [https://www.topsan.org/Proteins/RSGI/2ecc TOPSAN]</span></td></tr>
[[2ecc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1wjh 1wjh]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ECC OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/HOMEZ_HUMAN HOMEZ_HUMAN] May function as a transcriptional regulator.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ec/2ecc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ecc ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Inoue, M.]]
[[Category: Large Structures]]
[[Category: Kamatari, Y O.]]
[[Category: Inoue M]]
[[Category: Kigawa, T.]]
[[Category: Kamatari YO]]
[[Category: Kobayashi, N.]]
[[Category: Kigawa T]]
[[Category: Koshiba, S.]]
[[Category: Kobayashi N]]
[[Category: Li, H.]]
[[Category: Koshiba S]]
[[Category: Miyamoto, K.]]
[[Category: Li H]]
[[Category: Nameki, N.]]
[[Category: Miyamoto K]]
[[Category: Ohnishi, S.]]
[[Category: Nameki N]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Ohnishi S]]
[[Category: Tochio, N.]]
[[Category: Tochio N]]
[[Category: Yokoyama, S.]]
[[Category: Yokoyama S]]
[[Category: Dna binding protein]]
[[Category: Homeobox domain]]
[[Category: Homez]]
[[Category: Leucine zipper- containing factor]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
[[Category: Transcription factor]]

Latest revision as of 21:49, 29 May 2024

Solution Structure of the second Homeobox Domain of Human Homeodomain Leucine Zipper-Encoding Gene (Homez)Solution Structure of the second Homeobox Domain of Human Homeodomain Leucine Zipper-Encoding Gene (Homez)

Structural highlights

2ecc is a 1 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1wjh. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

HOMEZ_HUMAN May function as a transcriptional regulator.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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