2dzx: Difference between revisions

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-[[Image:2dzx.png|left|200px]]
-{{STRUCTURE_2dzx|  PDB=2dzx  |  SCENE=  }}
+==Structure of mutant tryptophan synthase alpha-subunit (E131-132A) from a hyperthermophile, Pyrococcus furiosus==
+<StructureSection load='2dzx' size='340' side='right'caption='[[2dzx]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2dzx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DZX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DZX FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dzx OCA], [https://pdbe.org/2dzx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dzx RCSB], [https://www.ebi.ac.uk/pdbsum/2dzx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dzx ProSAT], [https://www.topsan.org/Proteins/RSGI/2dzx TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TRPA_PYRFU TRPA_PYRFU] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dz/2dzx_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dzx ConSurf].
+<div style="clear:both"></div>
-===Structure of mutant tryptophan synthase alpha-subunit (E131-132A) from a hyperthermophile, Pyrococcus furiosus===
+==See Also==
+*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
-{{ABSTRACT_PUBMED_11118452}}
+__TOC__
+</StructureSection>
-==About this Structure==
+[[Category: Large Structures]]
-[[2dzx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DZX OCA].
-==Reference==
-<ref group="xtra">PMID:011118452</ref><references group="xtra"/>
-[[Category: Pyrococcus furiosus]]
-[[Category: Tryptophan synthase]]
-[[Category: Ogasahara, K.]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
-[[Category: Yamagata, Y.]]
-[[Category: Yutani, K.]]
-[[Category: Calorimetry]]
-[[Category: Hyperthermophile]]
-[[Category: Lyase]]
-[[Category: National project on protein structural and functional analyse]]
-[[Category: Nppsfa]]
 [[Category: Pyrococcus furiosus]]
-[[Category: Riken structural genomics/proteomics initiative]]
+[[Category: Ogasahara K]]
-[[Category: Rsgi]]
+[[Category: Yamagata Y]]
-[[Category: Stability]]
+[[Category: Yutani K]]
-[[Category: Structural genomic]]
-[[Category: Tryptophan synthase alpha-subunit]]
-[[Category: X-ray analysis]]