1x14: Difference between revisions
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==Crystal structure of E. coli transhydrogenase domain I with bound NAD== | |||
<StructureSection load='1x14' size='340' side='right'caption='[[1x14]], [[Resolution|resolution]] 1.94Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1x14]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X14 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X14 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x14 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x14 OCA], [https://pdbe.org/1x14 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x14 RCSB], [https://www.ebi.ac.uk/pdbsum/1x14 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x14 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PNTA_ECOLI PNTA_ECOLI] The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x1/1x14_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x14 ConSurf]. | |||
<div style="clear:both"></div> | |||
== | ==See Also== | ||
*[[NAD(P) transhydrogenase 3D structures|NAD(P) transhydrogenase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[ | |||
< | |||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Johansson | [[Category: Large Structures]] | ||
[[Category: Karlsson | [[Category: Johansson T]] | ||
[[Category: Krengel | [[Category: Karlsson BG]] | ||
[[Category: Okvist | [[Category: Krengel U]] | ||
[[Category: Oswald | [[Category: Okvist M]] | ||
[[Category: Pedersen | [[Category: Oswald C]] | ||
[[Category: Rydstrom | [[Category: Pedersen A]] | ||
[[Category: Tornroth | [[Category: Rydstrom J]] | ||
[[Category: Tornroth S]] | |||
Latest revision as of 16:35, 13 March 2024
Crystal structure of E. coli transhydrogenase domain I with bound NADCrystal structure of E. coli transhydrogenase domain I with bound NAD
Structural highlights
FunctionPNTA_ECOLI The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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