1xva: Difference between revisions
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==METHYLTRANSFERASE== | |||
<StructureSection load='1xva' size='340' side='right'caption='[[1xva]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
=== | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1xva]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XVA FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xva OCA], [https://pdbe.org/1xva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xva RCSB], [https://www.ebi.ac.uk/pdbsum/1xva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xva ProSAT]</span></td></tr> | ||
[[1xva]] is a 2 chain structure with sequence from [ | </table> | ||
== Function == | |||
== | [https://www.uniprot.org/uniprot/GNMT_RAT GNMT_RAT] Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine. | ||
< | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xv/1xva_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xva ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Fu | [[Category: Fu Z]] | ||
[[Category: Fujioka | [[Category: Fujioka M]] | ||
[[Category: Gomi | [[Category: Gomi T]] | ||
[[Category: Hu | [[Category: Hu Y]] | ||
[[Category: Konishi | [[Category: Konishi K]] | ||
[[Category: Ogawa | [[Category: Ogawa H]] | ||
[[Category: Takata | [[Category: Takata Y]] | ||
[[Category: Takusagawa | [[Category: Takusagawa F]] | ||
Latest revision as of 11:53, 14 February 2024
METHYLTRANSFERASEMETHYLTRANSFERASE
Structural highlights
FunctionGNMT_RAT Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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