1y1t: Difference between revisions

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[[Image:1y1t.png|left|200px]]


{{STRUCTURE_1y1t| PDB=1y1t | SCENE= }}
==Crystal Structure of the Uridine Phosphorylase from Salmonella Typhimurium at 1.77A Resolution==
<StructureSection load='1y1t' size='340' side='right'caption='[[1y1t]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1y1t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y1T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y1T FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y1t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y1t OCA], [https://pdbe.org/1y1t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y1t RCSB], [https://www.ebi.ac.uk/pdbsum/1y1t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y1t ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/UDP_SALTY UDP_SALTY] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/y1/1y1t_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1y1t ConSurf].
<div style="clear:both"></div>


===Crystal Structure of the Uridine Phosphorylase from Salmonella Typhimurium at 1.77A Resolution===
==See Also==
 
*[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[1y1t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y1T OCA].
[[Category: Large Structures]]
[[Category: Salmonella enterica subsp. enterica serovar typhimurium str. lt2]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
[[Category: Uridine phosphorylase]]
[[Category: Betzel C]]
[[Category: Betzel, C.]]
[[Category: Dontsova MV]]
[[Category: Dontsova, M V.]]
[[Category: Ealick SE]]
[[Category: Ealick, S E.]]
[[Category: Gabdoulkhakov AG]]
[[Category: Gabdoulkhakov, A G.]]
[[Category: Kachalova GS]]
[[Category: Kachalova, G S.]]
[[Category: Mikhailov AM]]
[[Category: Mikhailov, A M.]]
[[Category: Nucleoside phosphorylase]]
[[Category: Transcription]]

Latest revision as of 09:51, 23 August 2023

Crystal Structure of the Uridine Phosphorylase from Salmonella Typhimurium at 1.77A ResolutionCrystal Structure of the Uridine Phosphorylase from Salmonella Typhimurium at 1.77A Resolution

Structural highlights

1y1t is a 2 chain structure with sequence from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.77Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

UDP_SALTY Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1y1t, resolution 1.77Å

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