1vpa: Difference between revisions

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-[[Image:1vpa.png|left|200px]]
-{{STRUCTURE_1vpa|  PDB=1vpa  |  SCENE=  }}
+==Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (TM1393) from Thermotoga maritima at 2.67 A resolution==
+<StructureSection load='1vpa' size='340' side='right'caption='[[1vpa]], [[Resolution|resolution]] 2.67&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1vpa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VPA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VPA FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.67&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vpa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vpa OCA], [https://pdbe.org/1vpa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vpa RCSB], [https://www.ebi.ac.uk/pdbsum/1vpa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vpa ProSAT], [https://www.topsan.org/Proteins/JCSG/1vpa TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ISPD_THEMA ISPD_THEMA] Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vp/1vpa_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vpa ConSurf].
+<div style="clear:both"></div>
-===Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (TM1393) from Thermotoga maritima at 2.67 A resolution===
+==See Also==
+*[[MEP cytidylyltransferase 3D structures|MEP cytidylyltransferase 3D structures]]
+__TOC__
-==About this Structure==
+</StructureSection>
-[[1vpa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VPA OCA].
+[[Category: Large Structures]]
-[[Category: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase]]
 [[Category: Thermotoga maritima]]
-[[Category: JCSG, Joint Center for Structural Genomics.]]
-[[Category: 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase]]
-[[Category: Jcsg]]
-[[Category: Joint center for structural genomic]]
-[[Category: Protein structure initiative]]
-[[Category: Psi]]
-[[Category: Structural genomic]]
-[[Category: Tm1393]]
-[[Category: Transferase]]