1wq5: Difference between revisions

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-[[Image:1wq5.png|left|200px]]
-{{STRUCTURE_1wq5|  PDB=1wq5  |  SCENE=  }}
+==Crystal structure of tryptophan synthase alpha-subunit from Escherichia coli==
+<StructureSection load='1wq5' size='340' side='right'caption='[[1wq5]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1wq5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WQ5 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wq5 OCA], [https://pdbe.org/1wq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wq5 RCSB], [https://www.ebi.ac.uk/pdbsum/1wq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wq5 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wq5 TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TRPA_ECOLI TRPA_ECOLI] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wq/1wq5_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wq5 ConSurf].
+<div style="clear:both"></div>
-===Crystal structure of tryptophan synthase alpha-subunit from Escherichia coli===
+==See Also==
+*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
-{{ABSTRACT_PUBMED_15667212}}
+__TOC__
+</StructureSection>
-==About this Structure==
-[[1wq5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WQ5 OCA].
-==Reference==
-<ref group="xtra">PMID:015667212</ref><references group="xtra"/>
 [[Category: Escherichia coli]]
-[[Category: Tryptophan synthase]]
+[[Category: Large Structures]]
-[[Category: Ishizuka, M.]]
+[[Category: Ishizuka M]]
-[[Category: Morimoto, Y.]]
+[[Category: Morimoto Y]]
-[[Category: Nishio, K.]]
+[[Category: Nishio K]]
-[[Category: Ogasahara, K.]]
+[[Category: Ogasahara K]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+[[Category: Tsukihara T]]
-[[Category: Tsukihara, T.]]
+[[Category: Yutani K]]
-[[Category: Yutani, K.]]
-[[Category: Lyase]]
-[[Category: Riken structural genomics/proteomics initiative]]
-[[Category: Rsgi]]
-[[Category: Structural genomic]]
-[[Category: Tryptophan]]
-[[Category: Tryptophan synthase]]