1wcx: Difference between revisions

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-[[Image:1wcx.png|left|200px]]
-{{STRUCTURE_1wcx|  PDB=1wcx  |  SCENE=  }}
+==Crystal Structure of Mutant Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (L75M/I193M/L248M, SeMet derivative, Form-1 crystal)==
+<StructureSection load='1wcx' size='340' side='right'caption='[[1wcx]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-===Crystal Structure of Mutant Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (L75M/I193M/L248M, SeMet derivative, Form-1 crystal)===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1wcx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WCX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WCX FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-[[1wcx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WCX OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wcx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wcx OCA], [https://pdbe.org/1wcx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wcx RCSB], [https://www.ebi.ac.uk/pdbsum/1wcx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wcx ProSAT], [https://www.topsan.org/Proteins/RSGI/1wcx TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q5SKH2_THET8 Q5SKH2_THET8]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wc/1wcx_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wcx ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Thermus thermophilus]]
-[[Category: Uroporphyrinogen-III synthase]]
+[[Category: Kuramitsu S]]
-[[Category: Kuramitsu, S.]]
+[[Category: Matsuura T]]
-[[Category: Matsuura, T.]]
+[[Category: Mizohata E]]
-[[Category: Mizohata, E.]]
+[[Category: Murayama K]]
-[[Category: Murayama, K.]]
+[[Category: Sakai H]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+[[Category: Shirouzu M]]
-[[Category: Sakai, H.]]
+[[Category: Terada T]]
-[[Category: Shirouzu, M.]]
+[[Category: Yokoyama S]]
-[[Category: Terada, T.]]
-[[Category: Yokoyama, S.]]
-[[Category: Congenital erythropoietic porphyria]]
-[[Category: Lyase]]
-[[Category: Porphyrin]]
-[[Category: Riken structural genomics/proteomics initiative]]
-[[Category: Rsgi]]
-[[Category: Structural genomic]]
-[[Category: Uroporphyrinogen]]