1rjf: Difference between revisions
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==Structure of PPM1, a leucine carboxy methyltransferase involved in the regulation of protein phosphatase 2A activity== | |||
<StructureSection load='1rjf' size='340' side='right'caption='[[1rjf]], [[Resolution|resolution]] 2.25Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1rjf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RJF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RJF FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rjf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rjf OCA], [https://pdbe.org/1rjf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rjf RCSB], [https://www.ebi.ac.uk/pdbsum/1rjf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rjf ProSAT]</span></td></tr> | ||
[[1rjf]] is a 3 chain structure with sequence from [ | </table> | ||
== Function == | |||
== | [https://www.uniprot.org/uniprot/LCMT1_YEAST LCMT1_YEAST] Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. Acts on the two major protein phosphatase 2A catalytic subunits, PPH21 and PPH22.<ref>PMID:11060018</ref> <ref>PMID:11697862</ref> | ||
< | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rj/1rjf_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rjf ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Bettache | [[Category: Bettache N]] | ||
[[Category: Blondeau | [[Category: Blondeau K]] | ||
[[Category: Collinet | [[Category: Collinet B]] | ||
[[Category: Graille | [[Category: Graille M]] | ||
[[Category: Janin | [[Category: Janin J]] | ||
[[Category: Leulliot | [[Category: Leulliot N]] | ||
[[Category: Poupon | [[Category: Poupon A]] | ||
[[Category: Quevillon-Cheruel | [[Category: Quevillon-Cheruel S]] | ||
[[Category: | [[Category: Sorel I]] | ||
[[Category: | [[Category: De La Sierra-Gallay IL]] | ||
[[Category: Tilbeurgh | [[Category: Van Tilbeurgh H]] | ||