1sd6: Difference between revisions

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[[Image:1sd6.png|left|200px]]


{{STRUCTURE_1sd6|  PDB=1sd6  |  SCENE=  }}
==Crystal Structure of Native MecI at 2.65 A==
 
<StructureSection load='1sd6' size='340' side='right'caption='[[1sd6]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
===Crystal Structure of Native MecI at 2.65 A===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1sd6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SD6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SD6 FirstGlance]. <br>
{{ABSTRACT_PUBMED_15716455}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sd6 OCA], [https://pdbe.org/1sd6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sd6 RCSB], [https://www.ebi.ac.uk/pdbsum/1sd6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sd6 ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1sd6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SD6 OCA].  
== Function ==
 
[https://www.uniprot.org/uniprot/MECI_STAAU MECI_STAAU] Transcriptional repressor that constitutively blocks the transcription of the gene for the penicillin-binding protein MecA. Binds DNA as a dimer (By similarity).
==Reference==
== Evolutionary Conservation ==
<ref group="xtra">PMID:015716455</ref><references group="xtra"/>
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sd/1sd6_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sd6 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Archer, G L.]]
[[Category: Archer GL]]
[[Category: Musayev, F N.]]
[[Category: Musayev FN]]
[[Category: Robinson, H.]]
[[Category: Robinson H]]
[[Category: Safo, M K.]]
[[Category: Safo MK]]
[[Category: Scarsdale, N.]]
[[Category: Scarsdale N]]
[[Category: Zhao, Q.]]
[[Category: Zhao Q]]
[[Category: B-lactam]]
[[Category: Blai]]
[[Category: Dna binding protein]]
[[Category: Meci]]
[[Category: Methicillin]]
[[Category: Repressor]]

Latest revision as of 11:29, 14 February 2024

Crystal Structure of Native MecI at 2.65 ACrystal Structure of Native MecI at 2.65 A

Structural highlights

1sd6 is a 2 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.65Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MECI_STAAU Transcriptional repressor that constitutively blocks the transcription of the gene for the penicillin-binding protein MecA. Binds DNA as a dimer (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1sd6, resolution 2.65Å

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OCA