1sf2: Difference between revisions

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-[[Image:1sf2.png|left|200px]]
-{{STRUCTURE_1sf2|  PDB=1sf2  |  SCENE=  }}
+==Structure of E. coli gamma-aminobutyrate aminotransferase==
+<StructureSection load='1sf2' size='340' side='right'caption='[[1sf2]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1sf2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SF2 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sf2 OCA], [https://pdbe.org/1sf2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sf2 RCSB], [https://www.ebi.ac.uk/pdbsum/1sf2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sf2 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/GABT_ECOLI GABT_ECOLI] Catalyzes the transfer of the amino group from gamma-aminobutyrate (GABA) to alpha-ketoglutarate (KG) to yield succinic semialdehyde (SSA).<ref>PMID:20639325</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sf/1sf2_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sf2 ConSurf].
+<div style="clear:both"></div>
-===Structure of E. coli gamma-aminobutyrate aminotransferase===
+==See Also==
+*[[Aminotransferase 3D structures|Aminotransferase 3D structures]]
-{{ABSTRACT_PUBMED_15323550}}
+== References ==
+<references/>
-==About this Structure==
+__TOC__
-[[1sf2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SF2 OCA].
+</StructureSection>
-==Reference==
-<ref group="xtra">PMID:015323550</ref><ref group="xtra">PMID:016754985</ref><ref group="xtra">PMID:019146406</ref><references group="xtra"/>
-[[Category: 4-aminobutyrate transaminase]]
 [[Category: Escherichia coli]]
-[[Category: Carter, R J.]]
+[[Category: Large Structures]]
-[[Category: Fisher, A J.]]
+[[Category: Carter RJ]]
-[[Category: Langston, J A.]]
+[[Category: Fisher AJ]]
-[[Category: Liu, W.]]
+[[Category: Langston JA]]
-[[Category: Peterson, P E.]]
+[[Category: Liu W]]
-[[Category: Toney, M D.]]
+[[Category: Peterson PE]]
-[[Category: Zhou, X.]]
+[[Category: Toney MD]]
-[[Category: Aminotransferase]]
+[[Category: Zhou X]]
-[[Category: Transferase]]