1q5y: Difference between revisions

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-[[Image:1q5y.png|left|200px]]
-{{STRUCTURE_1q5y|  PDB=1q5y  |  SCENE=  }}
+==Nickel-Bound C-terminal Regulatory Domain of NikR==
+<StructureSection load='1q5y' size='340' side='right'caption='[[1q5y]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
-===Nickel-Bound C-terminal Regulatory Domain of NikR===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1q5y]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q5Y FirstGlance]. <br>
-{{ABSTRACT_PUBMED_12970756}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q5y OCA], [https://pdbe.org/1q5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q5y RCSB], [https://www.ebi.ac.uk/pdbsum/1q5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q5y ProSAT]</span></td></tr>
-[[1q5y]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q5Y OCA].
+</table>
+== Function ==
-==Reference==
+[https://www.uniprot.org/uniprot/NIKR_ECOLI NIKR_ECOLI] Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel.[HAMAP-Rule:MF_00476]
-<ref group="xtra">PMID:012970756</ref><references group="xtra"/>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q5/1q5y_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q5y ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
 [[Category: Escherichia coli]]
-[[Category: Chivers, P T.]]
+[[Category: Large Structures]]
-[[Category: Drennan, C L.]]
+[[Category: Chivers PT]]
-[[Category: Guo, Y.]]
+[[Category: Drennan CL]]
-[[Category: Sauer, R T.]]
+[[Category: Guo Y]]
-[[Category: Schreiter, E R.]]
+[[Category: Sauer RT]]
-[[Category: Sintchak, M D.]]
+[[Category: Schreiter ER]]
-[[Category: Beta sandwich]]
+[[Category: Sintchak MD]]
-[[Category: Metal binding protein]]
-[[Category: Nickel binding]]
-[[Category: Regulatory domain]]