1qyc: Difference between revisions

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[[Image:1qyc.png|left|200px]]


{{STRUCTURE_1qyc|  PDB=1qyc  |  SCENE=  }}
==Crystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases, and their relationship to isoflavone reductases==
 
<StructureSection load='1qyc' size='340' side='right'caption='[[1qyc]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===Crystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases, and their relationship to isoflavone reductases===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1qyc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pinus_taeda Pinus taeda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QYC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QYC FirstGlance]. <br>
{{ABSTRACT_PUBMED_13129921}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qyc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qyc OCA], [https://pdbe.org/1qyc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qyc RCSB], [https://www.ebi.ac.uk/pdbsum/1qyc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qyc ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1qyc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pinus_taeda Pinus taeda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QYC OCA].  
== Function ==
 
[https://www.uniprot.org/uniprot/PCBER_PINTA PCBER_PINTA] Oxidoreductase involved in lignan biosynthesis. Catalyzes the NADPH-dependent reduction of phenylcoumaran benzylic ethers. Converts dehydrodiconiferyl alcohol (DDC) to isodihydrodehydrodiconiferyl alcohol (IDDDC), and dihydrodehydrodiconiferyl alcohol (DDDC) to tetrahydrodehydrodiconiferyl alcohol (TDDC).<ref>PMID:10066819</ref> <ref>PMID:12369619</ref>
==Reference==
== Evolutionary Conservation ==
<ref group="xtra">PMID:013129921</ref><references group="xtra"/>
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qy/1qyc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qyc ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pinus taeda]]
[[Category: Pinus taeda]]
[[Category: Bedgar, D L.]]
[[Category: Bedgar DL]]
[[Category: Davin, L B.]]
[[Category: Davin LB]]
[[Category: Gang, D R.]]
[[Category: Gang DR]]
[[Category: Halls, S C.]]
[[Category: Halls SC]]
[[Category: Hilsenbeck, J L.]]
[[Category: Hilsenbeck JL]]
[[Category: Kang, C.]]
[[Category: Kang C]]
[[Category: Kasahara, H.]]
[[Category: Kasahara H]]
[[Category: Lawrence, P K.]]
[[Category: Lawrence PK]]
[[Category: Min, T.]]
[[Category: Min T]]
[[Category: Park, H.]]
[[Category: Park H]]
[[Category: Youn, B.]]
[[Category: Youn B]]
[[Category: Ifr]]
[[Category: Isoflavonoid]]
[[Category: Lignan]]
[[Category: Nadph-dependent aromatic alcohol reductase]]
[[Category: Pcber]]
[[Category: Plant protein]]
[[Category: Plr]]

Latest revision as of 11:18, 14 February 2024

Crystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases, and their relationship to isoflavone reductasesCrystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases, and their relationship to isoflavone reductases

Structural highlights

1qyc is a 2 chain structure with sequence from Pinus taeda. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PCBER_PINTA Oxidoreductase involved in lignan biosynthesis. Catalyzes the NADPH-dependent reduction of phenylcoumaran benzylic ethers. Converts dehydrodiconiferyl alcohol (DDC) to isodihydrodehydrodiconiferyl alcohol (IDDDC), and dihydrodehydrodiconiferyl alcohol (DDDC) to tetrahydrodehydrodiconiferyl alcohol (TDDC).[1] [2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Gang DR, Kasahara H, Xia ZQ, Vander Mijnsbrugge K, Bauw G, Boerjan W, Van Montagu M, Davin LB, Lewis NG. Evolution of plant defense mechanisms. Relationships of phenylcoumaran benzylic ether reductases to pinoresinol-lariciresinol and isoflavone reductases. J Biol Chem. 1999 Mar 12;274(11):7516-27. PMID:10066819 doi:10.1074/jbc.274.11.7516
  2. ↑ Shoji T, Winz R, Iwase T, Nakajima K, Yamada Y, Hashimoto T. Expression patterns of two tobacco isoflavone reductase-like genes and their possible roles in secondary metabolism in tobacco. Plant Mol Biol. 2002 Oct;50(3):427-40. PMID:12369619 doi:10.1023/a:1019867732278

1qyc, resolution 2.20Å

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