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[[Image:1jbl.png|left|200px]]


{{STRUCTURE_1jbl| PDB=1jbl |  SCENE= }}
==Solution structure of SFTI-1, A cyclic trypsin inhibitor from sunflower seeds==
<StructureSection load='1jbl' size='340' side='right'caption='[[1jbl]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1jbl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helianthus_annuus Helianthus annuus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JBL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JBL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PRD_001097:Trypsin+inhibitor+1'>PRD_001097</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jbl OCA], [https://pdbe.org/1jbl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jbl RCSB], [https://www.ebi.ac.uk/pdbsum/1jbl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jbl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SFTI1_HELAN SFTI1_HELAN] Inhibits trypsin, cathepsin G, elastase, chymotrypsin and thrombin. Does not inhibit factor Xa.<ref>PMID:10390350</ref>


===Solution structure of SFTI-1, A cyclic trypsin inhibitor from sunflower seeds===
==See Also==
 
*[[Trypsin inhibitor 3D structures|Trypsin inhibitor 3D structures]]
{{ABSTRACT_PUBMED_11493011}}
== References ==
 
<references/>
==About this Structure==
__TOC__
[[1jbl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Helianthus_annuus Helianthus annuus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JBL OCA].
</StructureSection>
 
==Reference==
<ref group="xtra">PMID:011493011</ref><references group="xtra"/>
[[Category: Helianthus annuus]]
[[Category: Helianthus annuus]]
[[Category: Anderson, M A.]]
[[Category: Large Structures]]
[[Category: Condie, B A.]]
[[Category: Anderson MA]]
[[Category: Craik, D J.]]
[[Category: Condie BA]]
[[Category: Korsinczky, M L.J.]]
[[Category: Craik DJ]]
[[Category: Otvos, L.]]
[[Category: Korsinczky MLJ]]
[[Category: Rosengren, K J.]]
[[Category: Otvos L]]
[[Category: Schirra, H J.]]
[[Category: Rosengren KJ]]
[[Category: West, J.]]
[[Category: Schirra HJ]]
[[Category: 1 disulfide bond]]
[[Category: West J]]
[[Category: 2 beta strand]]
[[Category: Cyclic backbone]]
[[Category: Protein binding]]
[[Category: Sfti-1]]

Latest revision as of 11:37, 7 February 2024

Solution structure of SFTI-1, A cyclic trypsin inhibitor from sunflower seedsSolution structure of SFTI-1, A cyclic trypsin inhibitor from sunflower seeds

Structural highlights

1jbl is a 1 chain structure with sequence from Helianthus annuus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SFTI1_HELAN Inhibits trypsin, cathepsin G, elastase, chymotrypsin and thrombin. Does not inhibit factor Xa.[1]

See Also

References

  1. ↑ Luckett S, Garcia RS, Barker JJ, Konarev AV, Shewry PR, Clarke AR, Brady RL. High-resolution structure of a potent, cyclic proteinase inhibitor from sunflower seeds. J Mol Biol. 1999 Jul 9;290(2):525-33. PMID:10390350 doi:10.1006/jmbi.1999.2891
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