1otp: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1otp.png|left|200px]]
-{{STRUCTURE_1otp|  PDB=1otp  |  SCENE=  }}
+==STRUCTURAL AND THEORETICAL STUDIES SUGGEST DOMAIN MOVEMENT PRODUCES AN ACTIVE CONFORMATION OF THYMIDINE PHOSPHORYLASE==
+<StructureSection load='1otp' size='340' side='right'caption='[[1otp]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-===STRUCTURAL AND THEORETICAL STUDIES SUGGEST DOMAIN MOVEMENT PRODUCES AN ACTIVE CONFORMATION OF THYMIDINE PHOSPHORYLASE===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1otp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OTP FirstGlance]. <br>
-{{ABSTRACT_PUBMED_9698549}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1otp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otp OCA], [https://pdbe.org/1otp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1otp RCSB], [https://www.ebi.ac.uk/pdbsum/1otp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1otp ProSAT]</span></td></tr>
-==About this Structure==
+</table>
-[[1otp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTP OCA].
+== Function ==
+[https://www.uniprot.org/uniprot/TYPH_ECOLI TYPH_ECOLI] The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
-==Reference==
+== Evolutionary Conservation ==
-<ref group="xtra">PMID:009698549</ref><references group="xtra"/>
+[[Image:Consurf_key_small.gif|200px|right]]
-[[Category: Escherichia coli]]
+Check<jmol>
-[[Category: Thymidine phosphorylase]]
+  <jmolCheckbox>
-[[Category: Cook, W J.]]
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ot/1otp_consurf.spt"</scriptWhenChecked>
-[[Category: Ealick, S E.]]
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-[[Category: Jasanoff, A.]]
+    <text>to colour the structure by Evolutionary Conservation</text>
-[[Category: Pugmire, M J.]]
+  </jmolCheckbox>
-[[Category: Walter, M R.]]
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1otp ConSurf].
-[[Category: Domain movement]]
+<div style="clear:both"></div>
-[[Category: Glycosyltransferase]]
+__TOC__
-[[Category: Phosphorylase]]
+</StructureSection>
-[[Category: Pyrimidine metabolism]]
+[[Category: Escherichia coli K-12]]
-[[Category: Salvage pathway]]
+[[Category: Large Structures]]
-[[Category: Transferase]]
+[[Category: Cook WJ]]
+[[Category: Ealick SE]]
+[[Category: Jasanoff A]]
+[[Category: Pugmire MJ]]
+[[Category: Walter MR]]