1fzi: Difference between revisions

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[[Image:1fzi.png|left|200px]]


{{STRUCTURE_1fzi| PDB=1fzi | SCENE= }}
==METHANE MONOOXYGENASE HYDROXYLASE, FORM I PRESSURIZED WITH XENON GAS==
<StructureSection load='1fzi' size='340' side='right'caption='[[1fzi]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1fzi]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Methylococcus_capsulatus Methylococcus capsulatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FZI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FZI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=XE:XENON'>XE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fzi OCA], [https://pdbe.org/1fzi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fzi RCSB], [https://www.ebi.ac.uk/pdbsum/1fzi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fzi ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MEMA_METCA MEMA_METCA] Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fz/1fzi_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fzi ConSurf].
<div style="clear:both"></div>


===METHANE MONOOXYGENASE HYDROXYLASE, FORM I PRESSURIZED WITH XENON GAS===
==See Also==
 
*[[Methane monooxygenase 3D structures|Methane monooxygenase 3D structures]]
{{ABSTRACT_PUBMED_11297413}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
[[1fzi]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Methylococcus_capsulatus Methylococcus capsulatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FZI OCA].
 
==Reference==
<ref group="xtra">PMID:011297413</ref><references group="xtra"/>
[[Category: Methane monooxygenase]]
[[Category: Methylococcus capsulatus]]
[[Category: Methylococcus capsulatus]]
[[Category: Frederick, C A.]]
[[Category: Frederick CA]]
[[Category: Lippard, S J.]]
[[Category: Lippard SJ]]
[[Category: Rosenzweig, A C.]]
[[Category: Rosenzweig AC]]
[[Category: Whittington, D A.]]
[[Category: Whittington DA]]
[[Category: Dinuclear iron center]]
[[Category: Monooxygenase]]
[[Category: Oxidoreductase]]

Latest revision as of 10:20, 7 February 2024

METHANE MONOOXYGENASE HYDROXYLASE, FORM I PRESSURIZED WITH XENON GASMETHANE MONOOXYGENASE HYDROXYLASE, FORM I PRESSURIZED WITH XENON GAS

Structural highlights

1fzi is a 6 chain structure with sequence from Methylococcus capsulatus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.3Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MEMA_METCA Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1fzi, resolution 3.30Å

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