3uci: Difference between revisions

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-[[Image:3uci.jpg|left|200px]]
-{{STRUCTURE_3uci|  PDB=3uci  |  SCENE=  }}
+==Crystal structure of Rhodostomin ARLDDL mutant==
+<StructureSection load='3uci' size='340' side='right'caption='[[3uci]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3uci]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UCI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UCI FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uci OCA], [https://pdbe.org/3uci PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uci RCSB], [https://www.ebi.ac.uk/pdbsum/3uci PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uci ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity).  Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).
-===Crystal structure of Rhodostomin ARLDDL mutant===
+==See Also==
+*[[Disintegrin|Disintegrin]]
+__TOC__
-==About this Structure==
+</StructureSection>
-[[3uci]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UCI OCA].
 [[Category: Calloselasma rhodostoma]]
-[[Category: Chang, Y S.]]
+[[Category: Large Structures]]
-[[Category: Chang, Y T.]]
+[[Category: Chang YS]]
-[[Category: Chen, C Y.]]
+[[Category: Chang YT]]
-[[Category: Chen, Y C.]]
+[[Category: Chen CY]]
-[[Category: Chuang, W J.]]
+[[Category: Chen YC]]
-[[Category: Huang, C H.]]
+[[Category: Chuang WJ]]
-[[Category: Shiu, J H.]]
+[[Category: Huang CH]]
-[[Category: Disintegrin]]
+[[Category: Shiu JH]]
-[[Category: Integrin alphavbeta3]]
-[[Category: Toxin]]