1el0: Difference between revisions

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[[Image:1el0.png|left|200px]]


{{STRUCTURE_1el0|  PDB=1el0  |  SCENE=  }}
==SOLUTION STRUCTURE OF THE HUMAN CC CHEMOKINE, I-309==
 
<StructureSection load='1el0' size='340' side='right'caption='[[1el0]]' scene=''>
===SOLUTION STRUCTURE OF THE HUMAN CC CHEMOKINE, I-309===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1el0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EL0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EL0 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1el0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1el0 OCA], [https://pdbe.org/1el0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1el0 RCSB], [https://www.ebi.ac.uk/pdbsum/1el0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1el0 ProSAT]</span></td></tr>
[[1el0]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EL0 OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/CCL1_HUMAN CCL1_HUMAN] Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8.<ref>PMID:1557400</ref>  
<ref group="xtra">PMID:010821677</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Category: Clark-Lewis, I.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Crump, M P.]]
Check<jmol>
[[Category: Keizer, D W.]]
  <jmolCheckbox>
[[Category: Lee, T W.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/el/1el0_consurf.spt"</scriptWhenChecked>
[[Category: Slupsky, C M.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Sykes, B D.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Chemokine fold]]
  </jmolCheckbox>
[[Category: Immune system]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1el0 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Clark-Lewis I]]
[[Category: Crump MP]]
[[Category: Keizer DW]]
[[Category: Lee TW]]
[[Category: Slupsky CM]]
[[Category: Sykes BD]]

Latest revision as of 13:03, 20 March 2024

SOLUTION STRUCTURE OF THE HUMAN CC CHEMOKINE, I-309SOLUTION STRUCTURE OF THE HUMAN CC CHEMOKINE, I-309

Structural highlights

1el0 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CCL1_HUMAN Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Miller MD, Krangel MS. The human cytokine I-309 is a monocyte chemoattractant. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):2950-4. PMID:1557400
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