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{{TOC limit|limit=2}}
{{TOC limit|limit=2}}
==Guide to Proteopedia Pages Concerning Hormones and their Receptors==
==Guide to Proteopedia Pages Concerning Hormones and their Receptors==
{{Structure
|PDB=
|SIZE=380|SCENE=Human_Follicle-Stimulating_Hormone_Complexed_with_its_Receptor/1fl7to1xwdmorph/4|CAPTION= FSH binding to the leucine-rich domain of Follicle Stimulating Hormone Receptor ([[1fl7]] morphing to [[1xwd]], [[resolution]] 2.92Å)
|SITE=
|LIGAND=
|ACTIVITY=
|GENE=
|DOMAIN=
|RELATEDENTRY=
|RESOURCES=
|COORDINATES=
}}
{{#tree:id=HormoneTopic|openlevels=0|
{{#tree:id=HormoneTopic|openlevels=0|
Articles in Proteopedia concerning [[Hormone]] include:
Articles in Proteopedia concerning [[Hormone]] include:
<!--* [[Follicle-stimulating hormone]] -->
* [[Hormones and their receptors]]
* [[Steroid Hormones and their receptors]]
* [[Signal transduction]]
* [[Sex steroids]]
* [[Steroids]]
* [[Human Follicle-Stimulating Hormone Complexed with its Receptor]]
* [[Human Follicle-Stimulating Hormone Complexed with its Receptor]]
* [[Estrogen receptor]]
* [[Estrogen-related receptor]]
* [[Estrogen-related receptor]]
* [[Androgen receptor|Androgen Receptor]]
* [[Leucine-rich repeat|Leucine-rich repeat proteins]]
* [[Leucine-rich repeat|Leucine-rich repeat proteins]]
* [[Human growth hormone]]
* [[Vascular Endothelial Growth Factor]]
* [[Vascular Endothelial Growth Factor]]
* [[Vascular Endothelial Growth Factor Receptor]]
* [[Vascular Endothelial Growth Factor Receptor]]
* [[Receiver domain of sensor histidine kinase CKI1]]
* [[Receiver domain of sensor histidine kinase CKI1]]
 
* [[Beta-2 Adrenergic Receptor]]
* [[Journal:JBSD:2|Neurotensin]]
* [[Neurotensin receptor]]
* [[Glucagon]]
* [[Glucagon receptor]]
* [[Hormone sensitive lipase]]
* [[Corticosteroid-binding globulin]]
* [[Erythropoietin]]
* [[Erythropoietin receptor]]
* [[Thyroid hormone receptor]]
}}
}}
<br />
<br />
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==Additional 3D Structures of Hormones and Hormone Receptors and Related Molecules==
==Additional 3D Structures of Hormones and Hormone Receptors and Related Molecules==
===Adrenaline===
[[Image:7tm labeled.png|right|400px]]
[[Beta-2 Adrenergic Receptor]]<br />
The human β2 adrenergic receptor bound to a [[hormone]] analog and G-protein ([[3sn6]]) is featured in an image on the right, and additional structures are on the [[Adrenergic receptor|Adrenergic receptor page]]. <br />
{{Template:GPCR3sn6}}
===Angiotensinogen===
===Angiotensinogen===
[[2wxw]], [[2wxx]], [[2wxy]], [[2wxz]], [[2wy0]], [[2wy1]], [[2x0b]]  - Angiotensinogen – human, rat, mouse<br /> 
[[Serpin]]   


===Chorionic Gonadotropin===
===Chorionic Gonadotropin===
[[1hrp]] - Chorionic Gonadotropin – human<br />
 
[[1hcn]] - Chorionic Gonadotropin – human<br />
[[1hrp]], [[1hcn]] - hCG – human<br />
[[1hd4]] - Alpha-subunit of Chorionic Gonadotropin – human<br />
[[1hd4]] - α-subunit of hCG <br />
[[1e9j]], [[1dz7]] - α-subunit of hCG - NMR<br />
[[1qfw]] - hCG + antibody<br />
 
=== Estrogen receptor ===
[[Estrogen receptor]]
 
===Estrogen-related Receptor===
[[Estrogen-related receptor]]
 
===Androgen Receptor===
[[Androgen receptor|Nuclear Androgen Receptor]]


===Follicle-Stimulating Hormone===
===Follicle-Stimulating Hormone===
[[1fl7]] - Follicle-Stimulating Hormone – human<br />
[[Follicle-stimulating hormone]]
[[1xwd]] - Human Follicle Stimulating Hormone complexed with its Receptor – human<br />
 
===PACAP/glucagon family of peptide hormones===
[[3n94]] - PAC1R, receptor of pituitary adenylate cyclase activating polypeptide, is a case of a crystal structure disagreeing with the NMR structure [[2jod]] and vice versa <br />
[[2jod]] - Pituitary adenylate cyclase-activating polypeptide (residues 6'-38') complexed to the extracellular 


===Glucocorticoid===
===Glucocorticoid===
[[3mne]], [[3mno]], [[3mnp]] - Glucocorticoid Receptor Ligand-binding Domain – human<br />
[[Glucocorticoid receptor]]


===Glucose-dependent Insulinotropic Polypeptide===
===Glucose-dependent Insulinotropic Polypeptide===
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===Growth Hormone===
===Growth Hormone===
[[3hhr]] -  Growth Hormone complexed with the extracellular portion of its receptor - human<br />
[[Human growth hormone]] is featured [[Human growth hormone|here]].<br />
[[1hwh]] -  Growth Hormone Mutant G120R complexed with the extracellular portion of its receptor - human<br />
[[1bp3]] - Growth Hormone complexed with the prolactin receptor - human<br />
[[3mjg]], [[3mjk]]  - Platelet-derived Growth Factor/Propeptide Complex and a Platelet-Derived Growth Factor/Receptor Complex  – human<br /> 
Vascular Endothelial Growth Factor – human and others, see [[VEGF#3D_Structures_of_VEGF|Vascular Endothelial Growth Factor Structures]]<br />
Vascular Endothelial Growth Factor Receptor – human, see [[VEGFR#Additional_3D_Structures_of_VEGFR|Vascular Endothelial Growth Factor Receptor Structures]]<br />
[[2xdg]] - Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor – human<br />


===Insulin===
===Insulin===
[[3ir0]] , [[1mso]]  , [[1trz]] , [[2qiu]] , [[2r34]], [[2r35]] , [[2r36]], [[3ilg]], [[2kjj]] , [[2kju]]  - Insulin – human<br />
[[Insulin]]
[[3nw5]],  [[3nw6]],  [[3nw7]] - insulin-like growth factor 1 receptor – human<br />
[[3loh]], [[2dtg]] - insulin receptor ectodomain  – human<br />
[[Glucose-dependent Insulinotropic Polypeptide Receptor]]
 
===Progesterone===
[[3hq5]],[[3g8n]], [[3g8o]], [[3hq5]] - Progesterone – human<br />
 
===Thyroid-Stimulating hormone===
[[3g04]] - TSH receptor in complex with a thyroid-stimulating autoantibody – human<br />
 
===Thyroid hormone===
[[2nll]] - DNA-Binding domain in complex with an inverted repeat class of thyroid response element– rat<br />
[[1xzx]]


===Thyroxine===
===Progesterone ===
[[2xn3]], [[2xn5]], [[2xn6]], [[2xn7]] - Thyroxine-binding Globulin  – human<br />


===Farnesoid X Receptor ===
[[1a28]] - hProgR steroid-binding domain + progesterone<br />
[[3olf]], [[3omk]], [[3omm]], [[3oof]], [[3ook]], [[3okh]], [[3oki]] - Farnesoid X Receptor  – human<br />
 
===PACAP/glucagon family of peptide hormones===
[[3n94]] - PAC1R, receptor of pituitary adenylate cyclase activating polypeptide, is a case of a crystal structure disagreeing with the NMR structure [[2jod]] and vice versa <br />
[[2jod]] -  Pituitary adenylate cyclase-activating polypeptide (residues 6'-38') complexed to the extracellular  domain of the human splice variant hPAC1-RS determined by NMR - human<br />
 
===Estrogen-related receptor===
Estrogen-related recepto – human and others, see [[Estrogen-related_receptor#3D_structures_of_estrogen-related_receptor|Estrogen-related receptor structures]]<br />
 
 
ADD [[3dzu]]


==See Also==
==See Also==
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* [[Membrane proteins]]
* [[Membrane proteins]]
* [[G protein-coupled receptor|G protein-coupled receptors]]
* [[G protein-coupled receptor|G protein-coupled receptors]]
 
* [[Nobel Prizes for 3D Molecular Structure]]
* [[Highest impact structures]] of all time
* [[Hormones and their receptors]]


==External Resources==
==External Resources==

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Wayne Decatur, Tomas Klumpler, Joel L. Sussman, Michal Harel, Alexander Berchansky
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