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[[Image:1oy5.gif|left|200px]]<br /><applet load="1oy5" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1oy5, resolution 2.60&Aring;" />
'''Crystal structure of tRNA (m1G37) methyltransferase from Aquifex aeolicus'''<br />


==About this Structure==
==Crystal structure of tRNA (m1G37) methyltransferase from Aquifex aeolicus==
1OY5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Active as [http://en.wikipedia.org/wiki/tRNA_(guanine-N(1)-)-methyltransferase tRNA (guanine-N(1)-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.31 2.1.1.31] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OY5 OCA].  
<StructureSection load='1oy5' size='340' side='right'caption='[[1oy5]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1oy5]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OY5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OY5 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oy5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oy5 OCA], [https://pdbe.org/1oy5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oy5 RCSB], [https://www.ebi.ac.uk/pdbsum/1oy5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oy5 ProSAT], [https://www.topsan.org/Proteins/BSGC/1oy5 TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TRMD_AQUAE TRMD_AQUAE] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oy/1oy5_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oy5 ConSurf].
<div style="clear:both"></div>


==Reference==
==See Also==
Crystal structure of tRNA (m1G37) methyltransferase from Aquifex aeolicus at 2.6 A resolution: a novel methyltransferase fold., Liu J, Wang W, Shin DH, Yokota H, Kim R, Kim SH, Proteins. 2003 Nov 1;53(2):326-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14517984 14517984]
*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
__TOC__
</StructureSection>
[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: tRNA (guanine-N(1)-)-methyltransferase]]
[[Category: Kim R]]
[[Category: BSGC, Berkeley Structural Genomics Center.]]
[[Category: Kim SH]]
[[Category: Kim, R.]]
[[Category: Liu J]]
[[Category: Kim, S H.]]
[[Category: Shin DH]]
[[Category: Liu, J.]]
[[Category: Wang W]]
[[Category: Shin, D H.]]
[[Category: Yokota H]]
[[Category: Wang, W.]]
[[Category: Yokota, H.]]
[[Category: berkeley structural genomics center]]
[[Category: bsgc structure funded by nih]]
[[Category: crystal structure]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomics]]
[[Category: trmd]]
[[Category: trna (m1g37) methyltransferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:23:08 2008''

Latest revision as of 10:10, 30 October 2024

Crystal structure of tRNA (m1G37) methyltransferase from Aquifex aeolicusCrystal structure of tRNA (m1G37) methyltransferase from Aquifex aeolicus

Structural highlights

1oy5 is a 3 chain structure with sequence from Aquifex aeolicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.6Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

TRMD_AQUAE Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1oy5, resolution 2.60Å

Drag the structure with the mouse to rotate

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