2gh7: Difference between revisions

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[[Image:2gh7.png|left|200px]]


{{STRUCTURE_2gh7|  PDB=2gh7  |  SCENE=  }}
==Epi-biotin complex with core streptavidin==
 
<StructureSection load='2gh7' size='340' side='right'caption='[[2gh7]], [[Resolution|resolution]] 1.00&Aring;' scene=''>
===Epi-biotin complex with core streptavidin===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2gh7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GH7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GH7 FirstGlance]. <br>
{{ABSTRACT_PUBMED_16699183}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=BTQ:EPI-BIOTIN'>BTQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gh7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gh7 OCA], [https://pdbe.org/2gh7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gh7 RCSB], [https://www.ebi.ac.uk/pdbsum/2gh7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gh7 ProSAT]</span></td></tr>
[[2gh7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GH7 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gh/2gh7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gh7 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Avidin|Avidin]]
*[[Avidin 3D structures|Avidin 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:016699183</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Streptomyces avidinii]]
[[Category: Streptomyces avidinii]]
[[Category: Aubert, D G.L.]]
[[Category: Aubert DGL]]
[[Category: Stenkamp, R E.]]
[[Category: Le Trong I]]
[[Category: Thomas, N R.]]
[[Category: Stenkamp RE]]
[[Category: Trong, I Le.]]
[[Category: Thomas NR]]
[[Category: Biotin]]
[[Category: Biotin binding protein]]
[[Category: Protein/ligand interaction]]
[[Category: Streptavidin]]

Latest revision as of 12:27, 14 February 2024

Epi-biotin complex with core streptavidinEpi-biotin complex with core streptavidin

Structural highlights

2gh7 is a 2 chain structure with sequence from Streptomyces avidinii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SAV_STRAV The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2gh7, resolution 1.00Å

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