3d4x: Difference between revisions

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-[[Image:3d4x.png|left|200px]]
-{{STRUCTURE_3d4x|  PDB=3d4x  |  SCENE=  }}
+==Crystal structure determination of cat (Felis silvestris catus) hemoglobin at 2.2 angstrom resolution==
+<StructureSection load='3d4x' size='340' side='right'caption='[[3d4x]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-===Crystal structure determination of cat (Felis silvestris catus) hemoglobin at 2.2 angstrom resolution===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3d4x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Felis_catus Felis catus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D4X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D4X FirstGlance]. <br>
-{{ABSTRACT_PUBMED_17909297}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d4x OCA], [https://pdbe.org/3d4x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d4x RCSB], [https://www.ebi.ac.uk/pdbsum/3d4x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d4x ProSAT]</span></td></tr>
-[[3d4x]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Felis_catus Felis catus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D4X OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/HBB_FELCA HBB_FELCA] Involved in oxygen transport from the lung to the various peripheral tissues.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d4/3d4x_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d4x ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Hemoglobin|Hemoglobin]]
+*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:017909297</ref><ref group="xtra">PMID:019255493</ref><ref group="xtra">PMID:019200047</ref><references group="xtra"/>
 [[Category: Felis catus]]
-[[Category: Balasubramanian, M.]]
+[[Category: Large Structures]]
-[[Category: Moorthy, Pon Sathya.]]
+[[Category: Balasubramanian M]]
-[[Category: Neelagandan, K.]]
+[[Category: Neelagandan K]]
-[[Category: Ponnuswamy, M N.]]
+[[Category: Ponnuswamy MN]]
-[[Category: Allosteric mechanism]]
+[[Category: Sathya Moorthy P]]
-[[Category: Felis silvestris catus]]
-[[Category: Heme]]
-[[Category: Hemoglobin]]
-[[Category: Iron]]
-[[Category: Low oxygen affinity]]
-[[Category: Monoclinic]]
-[[Category: Oxygen storage]]
-[[Category: Oxygen transport]]
-[[Category: Transport]]