3bxx: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| (5 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Binding of two substrate analogue molecules to dihydroflavonol 4-reductase alters the functional geometry of the catalytic site== | |||
<StructureSection load='3bxx' size='340' side='right'caption='[[3bxx]], [[Resolution|resolution]] 2.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3bxx]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Vitis_vinifera Vitis vinifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BXX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BXX FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=QUE:3,5,7,3,4-PENTAHYDROXYFLAVONE'>QUE</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bxx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bxx OCA], [https://pdbe.org/3bxx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bxx RCSB], [https://www.ebi.ac.uk/pdbsum/3bxx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bxx ProSAT]</span></td></tr> | ||
[[3bxx]] is a 6 chain structure with sequence from [ | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/DFRA_VITVI DFRA_VITVI] Bifunctional enzyme involved in flavonoid metabolism.[UniProtKB:Q9XES5] | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bx/3bxx_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bxx ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | ==See Also== | ||
*[[Ion channels|Ion channels]] | *[[Ion channels 3D structures|Ion channels 3D structures]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: | |||
[[Category: Vitis vinifera]] | [[Category: Vitis vinifera]] | ||
[[Category: Delrot | [[Category: Delrot S]] | ||
[[Category: | [[Category: Gallois B]] | ||
[[Category: | [[Category: Granier T]] | ||
[[Category: | [[Category: Langlois d'Estaintot B]] | ||
[[Category: Petit | [[Category: Petit P]] | ||
[[Category: Trabelsi | [[Category: Trabelsi N]] | ||
Latest revision as of 12:31, 21 February 2024
Binding of two substrate analogue molecules to dihydroflavonol 4-reductase alters the functional geometry of the catalytic siteBinding of two substrate analogue molecules to dihydroflavonol 4-reductase alters the functional geometry of the catalytic site
Structural highlights
FunctionDFRA_VITVI Bifunctional enzyme involved in flavonoid metabolism.[UniProtKB:Q9XES5] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
| ||||||||||||||||||